0000000000259270

AUTHOR

María José Martínez

showing 5 related works from this author

Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 count…

2022

© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: The 2015 Lancet Commission on global surgery identified surgery and anaesthesia as indispensable parts of holistic health-care systems. However, COVID-19 exposed the fragility of planned surgical services around the world, which have also been neglected in pandemic recovery planning. This study aimed to develop and validate a novel index to support local elective surgical system strengthening and address growing backlogs. Methods: First, we performed an international consultation through a four-stage consensus process to develop a multidomain index for hospital-level assess…

MaleHealth system resilience.*COVID-19/epidemiologySocial SciencesSağlık BilimleriGlobal HealthFundamental Medical SciencesClinical Medicine (MED)AnaesthesiasurgeryTIP GENEL & DAHİLİnisu navedene ključne riječiElective backlogMedicine and Health SciencesTOOLKlinik Tıp (MED)610 Medicine & healthMEDICINE GENERAL & INTERNAL11 Medical and Health SciencesKlinik Tıpsurgery; global surgery; health-care systemCovid19NIHR Global Health Unit on Global SurgeryGeneral MedicineHospitalsHospital preparedneTıphealth-care systemElective Surgical ProceduresHEALTH SYSTEMS*PandemicsMedicineFemaleLife Sciences & BiomedicineHumanHälso- och sjukvårdsorganisation hälsopolitik och hälsoekonomiTemel Tıp Bilimleri610 Medicine & healthglobal surgeryGenel TıpCAPACITYCOVIDSurg CollaborativeHospitalMedicine General & InternalGeneral & Internal MedicineHealth SciencesHumansPandemicsScience & TechnologyElective Surgical ProcedurePandemicKirurgiPlanned surgeryCOVID-19Health Care Service and Management Health Policy and Services and Health EconomyCLINICAL MEDICINESettore MED/18Settore MED/18 - Chirurgia Generaleelective surgeryHospital assessmentSystems strengtheningSurgeryHuman medicineMETHODOLOGY[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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The relationship between cortisol and cognitive function in healthy older people: The moderating role of Apolipoprotein E polymorphism.

2018

The Apolipoprotein E4 (ApoE-epsilon 4) allele has been suggested as the main risk factor for late onset Alzheimer's disease (AD), whereas the ApoE-epsilon 2 allele has been proposed as a protective factor. These proposals have increased the interest in the effect of the ApoE genotype in healthy people. Additionally, high cortisol levels have been related to negative effects on cognition. However, few studies have investigated the relationship between cognitive performance and cortisol, taking into account the different ApoE alleles. For this reason, the aim of this study was to evaluate different cognitive domains (declarative and working memory, attention, and executive function) and their…

Apolipoprotein EMaleSALIVARY CORTISOLHydrocortisonePituitary-Adrenal SystemCortisolBehavioral NeuroscienceExecutive FunctionPOSTTRAUMATIC-STRESS-DISORDER0302 clinical medicineCognitionGenotypeSOCIOECONOMIC-STATUSAttentionPOPULATIONeducation.field_of_study05 social sciencesNeuropsychologyCognitionMiddle AgedALZHEIMERS-DISEASElipids (amino acids peptides and proteins)FemaleApolipoprotein Emedicine.medical_specialtyHypothalamo-Hypophyseal SystemSEX-DIFFERENCESCognitive NeurosciencePopulationExperimental and Cognitive PsychologyPolymorphism Single Nucleotide050105 experimental psychology03 medical and health sciencesApolipoproteins EMemoryAWAKENING RESPONSEInternal medicinemedicineHumans0501 psychology and cognitive sciencesEffects of sleep deprivation on cognitive performanceAlleleeducationAgedELDERLYWorking memorybusiness.industryMEMORY PERFORMANCEE GENOTYPEBODY-MASS INDEXEndocrinologyOlder peoplebusinessNeuroscience030217 neurology & neurosurgeryNeurobiology of learning and memory
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Web Support for weight-loss interventions: PREDIRCAM2 clinical trial baseline characteristics and preliminary results

2018

An ongoing clinical trial is testing the efficacy of web telematic support in a structured program for obesity treatment and diabetes prevention. Participants were recruited from two tertiary-care hospitals and randomized to receive either a telematic intervention (TI) supported by PREDIRCAM2 web platform or a non-telematic intervention (NTI). All receive 1-year follow-up. Both interventions consist of tailored dietary and exercise prescriptions, based on a Mediterranean dietary pattern and general WHO exercise recommendations for adults. At 6 months, both groups have received 7 contacts, 3 exclusively telematic for the TI group. This is a preliminary result intention-to-treat analysis. One…

AdultMaleLifestyle modificationmedicine.medical_specialtyTelemedicine020205 medical informaticsMedicinaEndocrinology Diabetes and Metabolism02 engineering and technologyDiet MediterraneanBody Mass Index03 medical and health sciences0302 clinical medicineEndocrinologyLifestyle modificationDiabetes mellitusWeight Loss0202 electrical engineering electronic engineering information engineeringmedicineHumans030212 general & internal medicineHealthy LifestyleObesityExercise2. Zero hungerTelecomunicacionesbusiness.industryMiddle Agedmedicine.diseaseObesityMetabolic syndromeTelemedicine3. Good healthClinical trialMedical Laboratory TechnologyTreatment OutcomeWeight loss interventionsBaseline characteristicsPhysical therapyFemaleElectrónicaMetabolic syndromebusiness
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Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study

2021

We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors from outside their household. The primary outcome was postoperative pulmonary complications, adjusted in multivariable models for measured confounders. Pre-defined sub-group analyses were performed for the primary outcome. A total of 96,454 patients from 114 countries were included and overall, 26…

Lung DiseasesMaleInternationalitySARS-Cov-2 ; COVID-19 ; surgery ; pathways ; pre-operative isolationSettore MED/18 - CHIRURGIA GENERALEVascular damage Radboud Institute for Health Sciences [Radboudumc 16]pathwaysLung DiseaseESTUDOS PROSPECTIVOSCohort StudiesPatient IsolationsurgeryPostoperative Complications80 and overProspective StudiesProspective cohort study610 Medicine & healthAged 80 and overSARS-Cov-2; COVID-19; surgery; pathways; pre-operative isolationIncidence (epidemiology)Treatment OutcomeElective Surgical ProceduresFemaleElective Surgical ProcedureCohort studyHumanpre-operative isolationmedicine.medical_specialtyIsolation (health care)SARS-Cov-2Preoperative careNOCOVID-19; SARS-Cov-2; pathways; pre-operative isolation; surgeryAnesthesiologyPreoperative CaremedicineHumansElective surgeryLS7_4AgedElective Surgical Procedurebusiness.industrypathwayCOVID-19SurgeryReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]Prospective StudieAnesthesiology and Pain MedicineHuman medicinePostoperative ComplicationCohort Studiebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study

2021

SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk of venous thromboembolism. We conducted a planned sub-study and analysis from an international, multicentre, prospective cohort study of elective and emergency patients undergoing surgery during October 2020. Patients from all surgical specialties were included. The primary outcome measure was venous thromboembolism (pulmonary embolism or deep vein thrombosis) within 30 da…

Malepulmonary embolismInternationalitySettore MED/18 - CHIRURGIA GENERALEDeep veinVascular damage Radboud Institute for Health Sciences [Radboudumc 16]infectious diseasesCardiovascularSARS‐CoV‐2surgeryCOVID-19 ; SARS-CoV-2 ; deep vein thrombosis ; pulmonary embolism ; venous thromboembolismCohort StudiesPostoperative ComplicationsAnesthesiologyMedicine and Health SciencesProspective Studies610 Medicine & healthProspective cohort studyLung11 Medical and Health SciencesConfoundingHematologyMiddle AgedThrombosis17 Psychology and Cognitive SciencesCOVID-19; deep vein thrombosis; pulmonary embolism; SARS-CoV-2; venous thromboembolismPulmonary embolismCOVID-19; SARS-CoV-2; deep vein thrombosis; pulmonary embolism; venous thromboembolism.medicine.anatomical_structureCohortCOVID-19/complicationsPostoperative Complications/etiologyOriginal ArticleFemalePatient SafetyLife Sciences & BiomedicineCOVID-19; SARS-CoV-2; deep vein thrombosis; pulmonary embolism; venous thromboembolismHumanAdultmedicine.medical_specialtyAdolescentClinical Sciencesvenous thromboembolism610 Medicine & healthGlobalSurg CollaborativeVenous Thromboembolism/etiologydeep vein thrombosisNOCOVIDSurg CollaborativeYoung AdultMedicine General & InternalAge DistributionClinical ResearchCOVID‐19General & Internal MedicinemedicineHumansSex DistributionAgedScience & Technologybusiness.industrySARS-CoV-2PreventionNeurosciencesdeep vein thrombosiCOVID-19PneumoniaOdds ratioOriginal Articlesmedicine.diseaseSurgeryReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]Prospective StudieGood Health and Well BeingAnesthesiology and Pain MedicineHuman medicinePostoperative ComplicationCohort StudiebusinessVenous thromboembolism[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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