0000000000261973

AUTHOR

Carmen Valor Martínez

showing 4 related works from this author

Endothelium-dependent component in the contractile responses of human omental arteries to adrenergic stimulation

1993

Abstract The present study was designed to investigate the influence of endothelium-derived nitric oxide on the contractile responses of isolated human omental arteries to electrical field stimulation and noradrenaline. We measured isometric tension in artery rings obtained from portions of human omentum during the course of abdominal operations (32 patients). Electrical field stimulation induced frequency-dependent contractions which were abolished by tetrodotoxin (10−6 M) and prazosin (10−6 M), thus indicating that this effect was due to noradrenaline released from adrenergic nerves acting on α1-adrenoceptors. The increases in tension induced by electrical field stimulation were of greate…

AdultMalemedicine.medical_specialtyArginineEndotheliumIndomethacinTetrodotoxinIn Vitro TechniquesArginineNitric OxideMuscle Smooth VascularNitric oxideNorepinephrinechemistry.chemical_compoundInternal medicinemedicinePrazosinHumansAgedPharmacologybusiness.industryStereoisomerismArteriesMiddle AgedElectric StimulationNG-Nitroarginine Methyl EsterEndocrinologymedicine.anatomical_structurechemistryVasoconstrictionCirculatory systemTetrodotoxinFemaleEndothelium VascularbusinessOmentumMuscle Contractionmedicine.drugBlood vesselArteryEuropean Journal of Pharmacology
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Influence of Endothelial Nitric Oxide on Adrenergic Contractile Responses of Human Cerebral Arteries

1996

The present study was designed to investigate the influence of the endothelium and that of the L-arginine pathway on the contractile responses of isolated human cerebral arteries to electrical field stimulation (EFS) and norepinephrine. Rings of human middle cerebral artery were obtained during autopsy of 19 patients who had died 3–8 h before. EFS (1–8 Hz) induced frequency-dependent contractions that were abolished by tetrodotoxin, prazosin, and guanethidine (all at 10-6 M). The increases in tension were of greater magnitude in arteries denuded of endothelium. NG-monomethyl L-arginine (L-NMMA 10-4 M) potentiated the contractile response to EFS in artery rings with endothelium but did not …

AdultMalemedicine.medical_specialtySympathetic Nervous SystemEndotheliumIndomethacinCerebral arteriesIn Vitro TechniquesNitric Oxide030218 nuclear medicine & medical imagingNitric oxideNorepinephrine03 medical and health scienceschemistry.chemical_compound0302 clinical medicinemedicine.arteryInternal medicinePrazosinmedicineHumansGuanethidineAgedAged 80 and overomega-N-Methylargininebusiness.industryCerebral ArteriesMiddle AgedElectric Stimulationmedicine.anatomical_structureEndocrinologyNeurologychemistryVasoconstrictionAnesthesiaMiddle cerebral arterycardiovascular systemFemaleEndothelium VascularNeurology (clinical)Nitric Oxide SynthaseCardiology and Cardiovascular Medicinebusiness030217 neurology & neurosurgerymedicine.drugBlood vesselArteryJournal of Cerebral Blood Flow & Metabolism
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Assessment of Multilocus Sequence Analysis (MLSA) for Identification of Candidatus Liberibacter Solanacearum from Different Host Plants in Spain

2020

19 Pág.

0106 biological sciences0301 basic medicineMicrobiology (medical)MLSACitrusCandidatus Liberibacterzebra chipSequence analysisParsnipsSingle-nucleotide polymorphism01 natural sciencesMicrobiologyZebra chipArticlecitrus03 medical and health sciencesCarrotsLiberibacterCarrotVirologyH20 Plant diseasesPotatoesGeneParsniplcsh:QH301-705.5carrotGenetics<i>Liberibacter</i>biologyceleryHaplotypeCeleryRibosomal RNAbiology.organism_classificationHousekeeping geneZebra chipHLB030104 developmental biologylcsh:Biology (General)parsnippotatoPotato010606 plant biology & botanyMicroorganisms
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Gene polymorphisms and HLA-G expression in spontaneous abortions

2015

Abstract Introduction HLA-G and HLA-E are claimed to play a role in establishing maternal–fetal immune tolerance and in maintaining pregnancy. The presence of polymorphism in the HLA-G gene could cause a deficient or excessive expression of the HLA-G and HLA-E molecules. These anomalies could eventually cause pregnancy losses. Materials and methods Clinical study. A total of 90 patients were included in this study. These patients suffered spontaneous abortions between weeks 6 and 11 of pregnancy. We have analysed the most important polymorphisms of the HLA-G gene through different genetic studies and HLA-G and HLA-E expression through immunostaining in human cytotrophoblast cells from first…

PregnancyCytotrophoblastKaryotypeHuman leukocyte antigenBiologyAbortionmedicine.diseaseImmune toleranceAndrologymedicine.anatomical_structureHLA-GImmunologymedicineImmunostainingMedicina Reproductiva y Embriología Clínica
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