0000000000261999

AUTHOR

Janine Wilting

showing 2 related works from this author

A Pathway in the Brainstem for Roll-Tilt of the Subjective Visual Vertical: Evidence from a Lesion–Behavior Mapping Study

2012

The perceived subjective visual vertical (SVV) is an important sign of a vestibular otolith tone imbalance in the roll plane. Previous studies suggested that unilateral pontomedullary brainstem lesions cause ipsiversive roll-tilt of SVV, whereas pontomesencephalic lesions cause contraversive roll-tilts of SVV. However, previous data were of limited quality and lacked a statistical approach. We therefore tested roll-tilt of the SVV in 79 human patients with acute unilateral brainstem lesions due to stroke by applying modern statistical lesion–behavior mapping analysis. Roll-tilt of the SVV was verified to be a brainstem sign, and for the first time it was confirmed statistically that lesions…

MaleBrain Stem InfarctionsMedial vestibular nucleusBrain mappingFunctional LateralityOculomotor nucleusLesionPerceptual DisordersOcular Motility DisordersmedicineHumansAgedVestibular systemAged 80 and overBrain MappingGeneral NeuroscienceAnatomyMiddle AgedMedial longitudinal fasciculusMagnetic Resonance ImagingSuperior cerebellar pedunclemedicine.anatomical_structureSpace PerceptionVisual PerceptionFemaleBrainstemmedicine.symptomPsychologyBrief CommunicationsNeuroscience
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Vestibular thalamus: Two distinct graviceptive pathways.

2015

Objective: To determine whether there are distinct thalamic regions statistically associated with either contraversive or ipsiversive disturbance of verticality perception measured by subjective visual vertical (SVV). Methods: We used modern statistical lesion behavior mapping on a sample of 37 stroke patients with isolated thalamic lesions to clarify which thalamic regions are involved in graviceptive otolith processing and whether there are distinct regions associated with contraversive or ipsiversive SVV deviation. Results: We found 2 distinct systems of graviceptive processing within the thalamus. Contraversive tilt of SVV was associated with lesions to the nuclei dorsomedialis, intrala…

0301 basic medicineAdultMaleStroke patientNerve netThalamusBiologyBrain mappingFunctional LateralityLesion03 medical and health sciences0302 clinical medicineThalamusmedicineHumansAgedVestibular systemBrain MappingMiddle AgedStroke030104 developmental biologymedicine.anatomical_structureVestibuleSpace PerceptionFemaleNeurology (clinical)Vestibule Labyrinthmedicine.symptomNerve NetNeuroscience030217 neurology & neurosurgeryThalamic lesionsNeurology
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