0000000000262012
AUTHOR
Kirsten E. Zeuner
revised_supplementary_TAN-18-OR-0100 – Supplemental material for Structural brain network fingerprints of focal dystonia
Supplemental material, revised_supplementary_TAN-18-OR-0100 for Structural brain network fingerprints of focal dystonia by Venkata C. Chirumamilla, Christian Dresel, Nabin Koirala, Gabriel Gonzalez-Escamilla, Günther Deuschl, Kirsten E. Zeuner, Muthuraman Muthuraman and Sergiu Groppa in Therapeutic Advances in Neurological Disorders
Structural brain network fingerprints of focal dystonia
Background: Focal dystonias are severe and disabling movement disorders of a still unclear origin. The structural brain networks associated with focal dystonia have not been well characterized. Here, we investigated structural brain network fingerprints in patients with blepharospasm (BSP) compared with those with hemifacial spasm (HFS), and healthy controls (HC). The patients were also examined following treatment with botulinum neurotoxin (BoNT). Methods: This study included matched groups of 13 BSP patients, 13 HFS patients, and 13 HC. We measured patients using structural-magnetic resonance imaging (MRI) at baseline and after one month BoNT treatment, at time points of maximal and minim…
Grey Matter Microstructural Integrity Alterations in Blepharospasm Are Partially Reversed by Botulinum Neurotoxin Therapy.
OBJECTIVE Benign Essential Blepharospasm (BEB) and hemifacial spasm (HFS) are the most common hyperkinetic movement disorders of facial muscles. Although similar in clinical presentation different pathophysiological mechanisms are assumed. Botulinum Neurotoxin (BoNT) is a standard evidence-based treatment for both conditions. In this study we aimed to assess grey matter microstructural differences between these two groups of patients and compared them with healthy controls. In patients we furthermore tracked the longitudinal morphometric changes associated with BoNT therapy. We hypothesized microstructural differences between the groups at the time point of maximum symptoms representation a…
Supplementary_Figure_2 – Supplemental material for Structural brain network fingerprints of focal dystonia
Supplemental material, Supplementary_Figure_2 for Structural brain network fingerprints of focal dystonia by Venkata C. Chirumamilla, Christian Dresel, Nabin Koirala, Gabriel Gonzalez-Escamilla, Günther Deuschl, Kirsten E. Zeuner, Muthuraman Muthuraman and Sergiu Groppa in Therapeutic Advances in Neurological Disorders
sup1_inks_jpg – Supplemental material for Structural brain network fingerprints of focal dystonia
Supplemental material, sup1_inks_jpg for Structural brain network fingerprints of focal dystonia by Venkata C. Chirumamilla, Christian Dresel, Nabin Koirala, Gabriel Gonzalez-Escamilla, Günther Deuschl, Kirsten E. Zeuner, Muthuraman Muthuraman and Sergiu Groppa in Therapeutic Advances in Neurological Disorders
Supp1_jpg – Supplemental material for Structural brain network fingerprints of focal dystonia
Supplemental material, Supp1_jpg for Structural brain network fingerprints of focal dystonia by Venkata C. Chirumamilla, Christian Dresel, Nabin Koirala, Gabriel Gonzalez-Escamilla, Günther Deuschl, Kirsten E. Zeuner, Muthuraman Muthuraman and Sergiu Groppa in Therapeutic Advances in Neurological Disorders
Supp_figure_3_inkscape_png_jpg – Supplemental material for Structural brain network fingerprints of focal dystonia
Supplemental material, Supp_figure_3_inkscape_png_jpg for Structural brain network fingerprints of focal dystonia by Venkata C. Chirumamilla, Christian Dresel, Nabin Koirala, Gabriel Gonzalez-Escamilla, Günther Deuschl, Kirsten E. Zeuner, Muthuraman Muthuraman and Sergiu Groppa in Therapeutic Advances in Neurological Disorders