Author: Anna Cuppari

0000000000262516

AUTHOR

Anna Cuppari

0000-0002-7763-5747

showing 2 related works from this author

The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases

2019

© The Author(s) 2019.

0301 basic medicineProteasesProtein Conformationlcsh:MedicineAstacoideaCrystallography X-RayCleavage (embryo)Protein Structure SecondaryArticleMice03 medical and health sciencesScissile bondHydrolaseAnimalsHumansAmino Acid Sequencelcsh:ScienceProtein secondary structureX-ray crystallographyBinding SitesMultidisciplinary030102 biochemistry & molecular biologyChemistrylcsh:RMetalloendopeptidasesProteasesFetuinFetuin-BCell biologyZincFertility030104 developmental biologyProteolysisMetalloproteaseslcsh:QAstacinLinkerScientific Reports

researchProduct

Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition

2018

The co-crystal structure of the metallopeptidase astacin with its specific protein inhibitor fetuin-B reveals a novel mechanism of inhibition.

Crystallographymammalian fertilizationmetallopeptidaseResearch Papersstructure determination570 Life sciencesenzyme mechanismsprotein inhibitorQD901-999multi-protein complexessperm–egg fusionpolyspermyprotein structureX-ray crystallography570 Biowissenschaften

researchProduct

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