0000000000263590
AUTHOR
M. Salonen
Higher carotid-radial pulse wave velocity is associated with non-melancholic depressive symptoms in men - findings from Helsinki Birth Cohort Study
Background: Depression and cardiovascular disease (CVD) are major causes of global disease burden that are interrelated through mostly unknown mechanisms. We studied the relationship of melancholic and non-melancholic depressive symptoms with arterial stiffness, an important underlying mechanism of CVD. Methods: The Helsinki Birth Cohort Study recruited 683 previously extensively phenotyped subjects for this sub-study. Cross-sectional data along with responses regarding depressive symptoms were obtained for each participant. For evaluation of depressive symptoms, the Beck Depression Inventory (BDI)and subscales were used to measure melancholic and non-melancholic depressive symptoms. Arteri…
CHILDHOOD ADVERSITIES AND HOME ATMOSPHERE AS DETERMINANTS OF DISABILITY AND UNEMPLOYMENT PENSION
Childhood adversities have been linked with adverse life events, but less is known about the long-term effects of childhood home atmosphere in terms of work career. We investigated whether childhood adversities and home atmosphere were associated with disability or unemployment pension. In the Helsinki Birth Cohort Study (born 1934–44), 2001 cohort members had data available on 9 childhood home atmosphere items e.g. whether it was supportive or warm (sum score 0–36, higher score indicating more favorable atmosphere), and 9 childhood adversities e.g. unemployment, parent’s long-term illness or divorce (sum score 0–9, coded into no; one; and two or more) assessed in 2001–04. Of those, 1528 ha…
THE HEALTHY NORDIC DIET AMONG OLDER INDIVIDUALS PREDICTS INCIDENT DISABILITY IN A 10-YEAR FOLLOW-UP
We investigated whether adherence to the healthy Nordic diet among older individuals was associated with incident disability 10 years later. We studied 972 participants from the Helsinki Birth Cohort Study who were free of disability at baseline. At the mean age of 61 years the Nordic diet score (NDS) was calculated based on a validated food-frequency questionnaire that the participants filled in. Higher scores indicated better adherence to the healthy Nordic diet. At the mean age of 71 years, participants’ incident disability was assessed using a self-reported questionnaire and was based on two levels of disability: mobility difficulty (difficulty in walking 500 m) and self-care dependence…