0000000000263877

AUTHOR

Nicolaos Donos

showing 2 related works from this author

The effect of postsurgical administration of a selective cyclo-oxygenase-2 inhibitor on the healing of intrabony defects following treatment with ena…

2003

Regenerative treatment with enamel matrix proteins (EMD) has been shown to promote regeneration in intrabony periodontal defects. However, up to now various postoperative regimens such as the routine administration of nonsteroidal anti-inflammatory drugs (NSAIDs) were often used in combination with enamel matrix proteins. Therefore, it cannot be excluded that the results might have been influenced by the effect of the postoperative medication. The aim of this randomized, controlled, blinded, clinical investigation was to determine the effect of postsurgical administration of a selective cyclo-oxygenase-2 inhibitor on the healing of intrabony periodontal defects following regenerative period…

Malemedicine.medical_specialtyGingival and periodontal pocketBleeding on probingUrologyAlveolar Bone LossDentistryLactonesDental Enamel ProteinsOral administrationPeriodontal Attachment LossmedicineHumansPeriodontal PocketCyclooxygenase InhibitorsGingival RecessionSingle-Blind MethodSulfonesGeneral DentistryGingival recessionRofecoxibWound HealingCyclooxygenase 2 Inhibitorsbusiness.industryAnti-Inflammatory Agents Non-SteroidalDental Plaque IndexMembrane ProteinsIsoenzymesRegimenClinical attachment lossCyclooxygenase 2Prostaglandin-Endoperoxide SynthasesSystemic administrationGuided Tissue Regeneration PeriodontalFemalemedicine.symptomPeriodontal Indexbusinessmedicine.drugClinical oral investigations
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Five-year results following treatment of intrabony defects with enamel matrix proteins and guided tissue regeneration

2004

Treatment with enamel matrix proteins (EMD) or guided tissue regeneration (GTR) has been shown to enhance periodontal regeneration. However, until now there are limited data on the long-term results following these treatment modalities.The aim of the present clinical study was to present the 5-year results following treatment of intrabony defects with EMD, GTR, combination of EMD and GTR, and open flap debridement (OFD).Forty-two patients, each of whom displayed one intrabony defect of a probing depth of at least 6 mm, were randomly treated with one of the four treatment modalities. The following parameters were evaluated prior to surgery, at 1 year and at 5 years after: plaque index, gingi…

Bone RegenerationTreatment outcomeAlveolar Bone LossDentistryStatistics NonparametricRoot PlaningPrimary outcomeDental Enamel ProteinsHumansMedicineBone regenerationAnalysis of VarianceEnamel paintbusiness.industryOpen flap debridementRoot planingLong term resultsMiddle Agedvisual_artGuided Tissue Regeneration Periodontalvisual_art.visual_art_mediumPeriodonticsPeriodontal IndexbusinessEnamel matrix proteinsFollow-Up StudiesJournal of Clinical Periodontology
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