0000000000267979

AUTHOR

V. Marco

showing 3 related works from this author

HepatomiRNoma: The proposal of a new network of targets for diagnosis, prognosis and therapy in hepatocellular carcinoma

2015

Abstract: The diagnosis and treatment of hepatocellular carcinoma (HCC) underwent a huge advancement in the last years. Recently, microRNAs (miRNAs) have been also studied to provide a new tool for early diagnosis of high risk patients, for prognostic classification to identify those patients who benefit cancer treatment and for predictive definition to select the right targeted drug. In this review we revised all the available data obtained to explore the role of miRNAs in HCC. This analysis led to identification of miRNAs which could gain a diagnostic, prognostic or predictive role. The results of studies on miRNAs involved in HCC are initial and far from providing scientific evidences to…

Serum0301 basic medicineCarcinoma HepatocellularHepatocellular carcinomaPrognosimedicine.medical_treatmentBioinformaticsTargeted therapyTargeted therapy03 medical and health sciences0302 clinical medicinePrognostic classificationBiomarkers TumormedicineHumansProspective cohort studyHigh risk patientsbusiness.industryLiver NeoplasmsMicroRNAHematologyPrognosismedicine.diseaseCancer treatmentClinical PracticeMicroRNAs030104 developmental biologyOncology030220 oncology & carcinogenesisHepatocellular carcinomaHuman medicineDiagnosis; Hepatocellular carcinoma; MicroRNA; Prognosis; Serum; Targeted therapy; Hematology; Oncology; Geriatrics and GerontologyGeriatrics and GerontologybusinessDiagnosiCritical Reviews in Oncology/Hematology
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Influence of endothelial nitric oxide on neurogenic contraction of human pulmonary arteries.

1995

The present study was designed to investigate the contribution of the endothelium and that of the L-arginine pathway on the contractile responses of isolated human pulmonary arteries to electrical field stimulation (EFS) and noradrenaline. Isometric tension was measured in artery rings obtained from portions of human lung after thoracic surgery for removal of lung carcinoma (18 patients). Electrical field stimulation (EFS) induced frequency-dependent contractions of isolated human pulmonary arteries which were abolished by tetrodotoxin, guanethidine and prazosin (all at 10(-6) M). The increases in tension were of greater magnitude in arteries denuded of endothelium. NG-nitro-L-arginine meth…

Pulmonary and Respiratory MedicineGuanethidineMalemedicine.medical_specialtyEndotheliumTetrodotoxinIn Vitro TechniquesPulmonary ArteryArginineNitric OxideNitric oxidechemistry.chemical_compoundNorepinephrineInternal medicinemedicine.arterymedicinePrazosinHumansGuanethidineAgedDose-Response Relationship Drugbusiness.industryPrazosinElectric StimulationEndocrinologymedicine.anatomical_structureNG-Nitroarginine Methyl EsterchemistryAnesthesiaPulmonary arteryCirculatory systemEndothelium VascularNitric Oxide SynthasebusinessAdrenergic FibersAdrenergic alpha-AgonistsBlood vesselmedicine.drugArteryMuscle ContractionThe European respiratory journal
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Tratamiento quirúrgico de las roturas del tendón de Aquiles

2000

El objetivo del trabajo fue valorar los resultados y complicaciones obtenidos tras tratamiento quirúrgico de las rupturas subcutáneas del tendón de Aquiles. Se revisaron 26 pacientes, con un seguimiento mínimo de 1 año. Detallamos nuestra metodología en cuanto a técnica quirúrgica y manejo postoperatorio. Se valoró el resultado clínico según los siguientes parámetros: movilidad de tobillo, potencia muscular tríceps, engrosamiento tendinoso, claudicación a la marcha, atrofia gemelar, incorporación a actividades deportivas y alteraciones residuales. Los resultados fueron muy buenos en 21 casos (80,7%); buenos en 5 (19,3%), y ningún caso con resultado regular o malo. Destacamos 5 complicacione…

Medicina clínicaUNESCO::CIENCIAS MÉDICAS:CIENCIAS MÉDICAS [UNESCO]Ciencias de la salud
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