0000000000277017
AUTHOR
Lars Gidskehaug
Genome-wide association mapping for milk fat composition and fine mapping of a QTL for de novo synthesis of milk fatty acids on bovine chromosome 13
Background Bovine milk is widely regarded as a nutritious food source for humans, although the effects of individual fatty acids on human health is a subject of debate. Based on the assumption that genomic selection offers potential to improve milk fat composition, there is strong interest to understand more about the genetic factors that influence the biosynthesis of bovine milk and the molecular mechanisms that regulate milk fat synthesis and secretion. For this reason, the work reported here aimed at identifying genetic variants that affect milk fatty acid composition in Norwegian Red cattle. Milk fatty acid composition was predicted from the nation-wide recording scheme using Fourier tr…
MOESM1 of Genome-wide association mapping for milk fat composition and fine mapping of a QTL for de novo synthesis of milk fatty acids on bovine chromosome 13
Additional file 1: Table S1. SNPs genotyped for the candidate gene map, with rs numbers, positions in base pairs and primer sequences.
MOESM4 of Genome-wide association mapping for milk fat composition and fine mapping of a QTL for de novo synthesis of milk fatty acids on bovine chromosome 13
Additional file 4: Table S4. Results from single-marker association analyses on BTA13 data from the BovineHD BeadChip.
MOESM2 of Genome-wide association mapping for milk fat composition and fine mapping of a QTL for de novo synthesis of milk fatty acids on bovine chromosome 13
Additional file 2: Table S2. Results for calibration of FTIR-spectra against GC-FID reference data, correlations between each FA and total fat percentage, and estimates of variance components with standard errors.
MOESM3 of Genome-wide association mapping for milk fat composition and fine mapping of a QTL for de novo synthesis of milk fatty acids on bovine chromosome 13
Additional file 3: Table S3. GWAS results.
MOESM5 of Genome-wide association mapping for milk fat composition and fine mapping of a QTL for de novo synthesis of milk fatty acids on bovine chromosome 13
Additional file 5: Table S5. Results from single-marker association analyses on SNPs in the candidate gene region.