0000000000278183

AUTHOR

Romano Tetamo

showing 6 related works from this author

Epidemiology of intensive care unit-acquired sepsis in Italy: Results of the SPIN-UTI network

2018

Background. Sepsis is the major cause of mortality from any infectious disease worldwide. Sepsis may be the result of a healthcare associated infection (HAI): the most frequent adverse events during care delivery especially in Intensive Care Units (ICUs). The main aim of the present study was to describe the epidemiology of ICU-acquired sepsis and related outcomes among patients enrolled in the framework of the Italian Nosocomial Infections Surveillance in ICUs - SPIN-UTI project. Study design. Prospective multicenter study. Methods. The SPIN-UTI network adopted the European protocols for patient-based HAI surveillance. Results. During the five editions of the SPIN-UTI project, from 2008 to…

Sleep Initiation and Maintenance DisorderMaleTime FactorsHealthcare-associated infections; Mortality; Sepsis; Surveillance; Public Health Environmental and Occupational Health; Infectious DiseasesDiet MediterraneanCoffeeHealth StatuHealthcare-associated infections; Mortality Parole chiave: Infezioni correlate all'assistenza; Mortalità; Sepsi; Sepsis; Sorveglianza; Surveillance; Public Health Environmental and Occupational Health; Infectious DiseasesAcademic PerformancePrevalenceSurveys and QuestionnaireHospital MortalityProspective StudiesCross InfectionSurveillanceIncidenceSmokingTryptophanShockMiddle AgedShock SepticMortalitàIntensive Care UnitsInfectious DiseasesItalyPopulation SurveillanceFemalePublic HealthHumanAdultEmploymentAlcohol DrinkingSepsiIntensive Care UnitHealthcare-associated infectionsRegression AnalysiYoung AdultAge DistributionSepsisLearningHumansHealthcare-associated infectionMortalityExerciseLife StyleSettore MED/42 - IGIENE GENERALE E APPLICATAAgedCross-Sectional StudieHealthcare-associated infections; Mortality; Sepsis; SurveillanceSepticEnvironmental and Occupational HealthBody WeightLength of StayBody HeightProspective StudieSorveglianzaQuality of LifeStudents NursingMortality Parole chiave: Infezioni correlate all'assistenza
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Co-colonization with carbapenem-resistant Klebsiella pneumoniae and Acinetobacter baumannii in intensive care unit patients

2013

Objectives: This investigation was conducted to study co-colonization by carbapenem-resistant Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-Kp) and Acinetobacter baumannii (CRAB) in intensive care unit (ICU) patients in Palermo, Sicily, a geographic area where both organisms are endemic in the healthcare setting. Risk factors at admission and during ICU stay and outcomes were also evaluated. Methods: All patients colonized by KPC-Kp, or CRAB, or both in 2 ICUs of a large general hospital during the period October 2011 – March 2012 were enrolled. Demographics and clinical data were collected. Resistance determinants and clonality of the 2 organisms were characterized by mo…

Acinetobacter baumanniiAdultMaleMicrobiology (medical)medicine.medical_specialtyPediatricsYounger ageGenotypeCarbapenem resistant Klebsiella pneumoniaeKlebsiella pneumoniaeCritical IllnessSettore MED/42 - Igiene Generale E ApplicataHospitals Generalbeta-Lactamaseslaw.inventionBacterial ProteinsRisk FactorslawInternal medicineDrug Resistance BacterialmedicineHumansGeneral hospitalSicilyAgedAged 80 and overGeneral Immunology and MicrobiologybiologyCoinfectionbusiness.industryMajor traumaGeneral MedicineMiddle Agedbiology.organism_classificationmedicine.diseaseIntensive care unitCarbapenem resistance co-colonization intensive care unit risk factorsKlebsiella InfectionsAcinetobacter baumanniiMolecular TypingIntensive Care UnitsKlebsiella pneumoniaeInfectious DiseasesFemaleCo colonizationbusinessAcinetobacter InfectionsScandinavian Journal of Infectious Diseases
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Ongoing spread of colistin-resistant Klebsiella pneumoniae in different wards of an acute general hospital, Italy, June to December 2011.

2012

We describe polyclonal spread of colistin-resistant Klebsiella pneumoniae in an acute general hospital in Italy. Between June and December 2011, 58 colistin-resistant K. pneumoniae isolates were recovered from 28 patients admitted to different wards, but mainly in the intensive care units. All isolates were tested for drug susceptibility and the presence of beta-lactamase (bla) genes. Clonality was investigated by repetitive extragenic palindromic (rep)-PCR and multilocus sequence typing (MLST). Fifty-two isolates had minimum inhibitory concentrations (MICs) for colistin of 6-128 mg/L, carried blaKPC3 and were attributed to sequence type ST258. The remaining six isolates were susceptible to…

DNA BacterialSettore MED/07 - Microbiologia E Microbiologia ClinicaEpidemiologyKlebsiella pneumoniaeMicrobial Sensitivity TestsSettore MED/42 - Igiene Generale E ApplicataHospitals GeneralPolymerase Chain ReactionKlebsiella pneumoniae carbapenems colistin resistance ICU epidemiologybeta-LactamasesMicrobiologyDisease OutbreaksAntibiotic resistanceVirologyIntensive careDrug Resistance Multiple BacterialPatients' RoomsMedicineHumansKlebsiella pneumoniae; colistin-resistance; MLSTGeneral hospitalCross Infectionbiologybusiness.industryColistinPublic Health Environmental and Occupational HealthOutbreakbiochemical phenomena metabolism and nutritionbiology.organism_classificationAnti-Bacterial AgentsBacterial Typing TechniquesKlebsiella InfectionsIntensive Care UnitsKlebsiella pneumoniaeCarbapenemsItalyColistinMultilocus sequence typingbusinessHorizontal transmissionmedicine.drugMultilocus Sequence TypingEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
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Evolution Over Time of Ventilatory Management and Outcome of Patients With Neurologic Disease

2021

OBJECTIVES: To describe the changes in ventilator management over time in patients with neurologic disease at ICU admission and to estimate factors associated with 28-day hospital mortality. DESIGN: Secondary analysis of three prospective, observational, multicenter studies. SETTING: Cohort studies conducted in 2004, 2010, and 2016. PATIENTS: Adult patients who received mechanical ventilation for more than 12 hours. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Among the 20,929 patients enrolled, we included 4,152 (20%) mechanically ventilated patients due to different neurologic diseases. Hemorrhagic stroke and brain trauma were the most common pathologies associated with the need fo…

Malemedicine.medical_treatmentpulmonary complicationsRESPIRATORY-DISTRESS-SYNDROMECritical Care and Intensive Care MedicineCASE-FATALITY0302 clinical medicineRisk FactorsBrain Injuries TraumaticMulticenter Studies as TopicHospital MortalityProspective StudiesSimplified Acute Physiology ScoreStrokePOPULATIONSimplified Acute Physiology ScoreAge FactorsANEURYSMAL SUBARACHNOID HEMORRHAGEMiddle AgedHemorrhagic StrokeIntensive Care UnitsObservational Studies as TopicAnesthesiaBreathingFemalemedicine.symptomVentilator WeaningCohort studyAdultTRAUMATIC BRAIN-INJURYPressure support ventilationmechanical ventilationprognosis factorsACUTE LUNG INJURY03 medical and health sciencesmedicineHumansAgedIschemic StrokeMechanical ventilationNoninvasive Ventilationbusiness.industryMORTALITYneurologic patientsOrgan dysfunction030208 emergency & critical care medicineLength of Staymedicine.diseaseTRENDSRespiration Artificial030228 respiratory systemEtiologyNEUROCRITICAL CARENervous System DiseasesTracheotomybusinessCritical Care Medicine
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Epidemiology and clonality of carbapenem-resistant Acinetobacter baumannii from an intensive care unit in Palermo, Italy

2012

Abstract Background Multidrug-resistant Acinetobacter baumannii, initially considered as having a poor clinical relevance, is frequently isolated from infection cases in intensive care units. We describe the epidemiology of carbapenem resistant A. baumannii (CRAB) in a general ICU in Palermo, Italy, from October 2010 to March 2011. Findings 58 of 61 isolates exhibited MICs for meropenem or imipenem ≥16 mg/L. Forty-nine carried blaOXA-23 and two blaOXA-58 genes. Five subtype clusters were detected by rep-PCR. Clusters D and E included 10 isolates that tested negative for the carbapenem resistance genes. MLST attributed all isolates, but two, with sequence type (ST)2, whereas the two remainin…

MaleAcinetobacter baumanniiImipenemSettore MED/07 - Microbiologia E Microbiologia ClinicaTime Factorslcsh:MedicineTigecyclinePolymerase Chain Reactionintensive care unitlaw.inventionlawDrug Resistance Multiple BacterialEpidemiologypolycyclic compoundsMedicinelcsh:QH301-705.5Medicine(all)Aged 80 and overbiologyGeneral MedicineMiddle AgedIntensive care unitAcinetobacter baumanniiIntensive Care UnitsItalyFemaleAcinetobacter baumannii; intensive care unitAcinetobacter Infectionsmedicine.drugAdultmedicine.medical_specialtyAdolescentShort ReportMicrobial Sensitivity TestsMeropenemGeneral Biochemistry Genetics and Molecular BiologyYoung AdultIntensive careHumansIntensive care medicinelcsh:Science (General)AgedDemographyBiochemistry Genetics and Molecular Biology(all)business.industrylcsh:Rbiochemical phenomena metabolism and nutritionbacterial infections and mycosesbiology.organism_classificationClone CellsCarbapenemslcsh:Biology (General)bacteriabusinessCarbapenem resistant Acinetobacter baumanniilcsh:Q1-390BMC Research Notes
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Outbreak of infection with Klebsiella pneumoniae sequence type 258 producing Klebsiella pneumoniae Carbapenemase 3 in an intensive care unit in Italy

2010

Gram-negative pathogens producing carbapenemases represent an alarming clinical threat with serious effects on patient outcomes ([3][1], [7][2]). In 2001, Yigit et al. ([11][3]) reported a novel β-lactamase termed “ K lebsiella pneumoniae carbapenemase” (KPC-1) in North Carolina. KPC-producing

Microbiology (medical)AdultMaleSettore MED/07 - Microbiologia E Microbiologia ClinicaAdolescentGenotypeKlebsiella pneumoniaemedicine.medical_treatmentTreatment outcomeMicrobial Sensitivity TestsKlebsiella pneumoniae carbapenem UTI outbreakbeta-Lactamaseslaw.inventionDisease courseMicrobiologyDisease OutbreaksBacterial proteinBacterial Proteinslawpolycyclic compoundsMedicineHumansLetters to the EditorAgedAged 80 and overbiologybusiness.industryOutbreakKlebsiella infectionsSequence Analysis DNAMiddle Agedbacterial infections and mycosesbiology.organism_classificationIntensive care unitDNA FingerprintingAnti-Bacterial AgentsBacterial Typing TechniquesKlebsiella InfectionsIntensive Care UnitsKlebsiella pneumoniaeTreatment OutcomeItalyBeta-lactamaseFemalebusiness
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