6533b7d2fe1ef96bd125dd2e
RESEARCH PRODUCT
Epidemiology of intensive care unit-acquired sepsis in Italy: Results of the SPIN-UTI network
Antonella AgodiM. BarchittaF. AuxiliaS. BrusaferroM. M. D'erricoM. T. MontagnaC. PasquarellaS. TardivoC. ArrigoniL. FabianiP. LaurentiA. R. MattalianoG. B. OrsiR. SqueriM. V. TorregrossaI. MuraMary Rose AielloCristina AllianiMaria Rita AmatucciManuela AntociMassimo AntonelliMarinella AstutoLuca ArnoldoBenedetto ArruGiorgio BaccariPamela BarbadoroAndrea BarbaraCynthia BarilaroPietro BattagliaPatrizia BellocchiMara Olga BernasconiAida BiancoEmanuela BissoloAnna BocchiAnna BrunoMarco BrusaferroMargherita BuccheriFrancesca CampanellaRosario CaninoAntonino CannistràSanta Adele CariniSebastiano CatalanoPaola CastellaniGiacomo CastiglioneSalvatore ConiglioCiriaco ConsolanteCarmela ConteRoberta ContriscianiRosy CoralliniPatricia CrollariGianfranco DamianiCarmelo DenaroSanta De RemigisFrancesca DianaRosario Di BartoloAntonino Di BenedettoGianna Di FabioCarlo Di FalcoVito DigeronimoPietro Di GregorioRoberta DistefanoGiovanni EgittoElena FalcianiPatrizia FarruggiaSalesia FenaroliGiuseppe FerlazzoGiuseppe GarofaloMassimo GirardisLinda GiovanelliGabriele GiubbiniAdriana GraceffaAntonina GuadagnaGiovanna GreguFranco IngalaLudovico InnocenziGiuseppa La CameraMaria Clara La RosaLucia LesaAnna Maria LonghitanoGiuseppe LuppinoCarmelo Massimo MaidaGiuseppe MantaGiovanni MarinoMaria Dolores MasiaRiccardo MavigliaMagda MazzettiAndrea MaugeriMaria Teresa MegnaLaura Maria MellaMarina MilazzoMario MiliaCaterina MinariMassimo MinervaMarco MordacciPaola MurgiaPietro OliveriMaria Patrizia OloriRiccardo PagliaruloRosanna PalermoIrene PandianiFederico PappalardoCristina PapettiAdolfo PartenzaDiana PascuMarcello PasculliMaria PaviaMaria Luisa PavoneMaria Giovanna PellegrinoFabrizio PelligraDanila PillonSergio PintaudiLucia PitzoiAndrea PintoPaola PiottiSimona PupoRosalba QuattrocchiElena RighiAlberto RigoAnnalisa RigoAntonina RomeoEmilio RosaSerafina RutiglianoPierangelo SarchiGuglielmo ScimonelloAntonello SeminerioPaolo StefaniniGiovanna SticcaStefania TaddeiLorella TessariRomano TetamoMariantonietta TiccaSalvatore TribastoniSarah ValloraniFederica VenturoniEmilia VitaglianoPietro VitaliAssunta ZapponeEttore ZeiMaria Prudenzia Zeolisubject
Sleep Initiation and Maintenance DisorderMaleTime FactorsHealthcare-associated infections; Mortality; Sepsis; Surveillance; Public Health Environmental and Occupational Health; Infectious DiseasesDiet MediterraneanCoffeeHealth StatuHealthcare-associated infections; Mortality Parole chiave: Infezioni correlate all'assistenza; Mortalità; Sepsi; Sepsis; Sorveglianza; Surveillance; Public Health Environmental and Occupational Health; Infectious DiseasesAcademic PerformancePrevalenceSurveys and QuestionnaireHospital MortalityProspective StudiesCross InfectionSurveillanceIncidenceSmokingTryptophanShockMiddle AgedShock SepticMortalitàIntensive Care UnitsInfectious DiseasesItalyPopulation SurveillanceFemalePublic HealthHumanAdultEmploymentAlcohol DrinkingSepsiIntensive Care UnitHealthcare-associated infectionsRegression AnalysiYoung AdultAge DistributionSepsisLearningHumansHealthcare-associated infectionMortalityExerciseLife StyleSettore MED/42 - IGIENE GENERALE E APPLICATAAgedCross-Sectional StudieHealthcare-associated infections; Mortality; Sepsis; SurveillanceSepticEnvironmental and Occupational HealthBody WeightLength of StayBody HeightProspective StudieSorveglianzaQuality of LifeStudents NursingMortality Parole chiave: Infezioni correlate all'assistenzadescription
Background. Sepsis is the major cause of mortality from any infectious disease worldwide. Sepsis may be the result of a healthcare associated infection (HAI): the most frequent adverse events during care delivery especially in Intensive Care Units (ICUs). The main aim of the present study was to describe the epidemiology of ICU-acquired sepsis and related outcomes among patients enrolled in the framework of the Italian Nosocomial Infections Surveillance in ICUs - SPIN-UTI project. Study design. Prospective multicenter study. Methods. The SPIN-UTI network adopted the European protocols for patient-based HAI surveillance. Results. During the five editions of the SPIN-UTI project, from 2008 to 2017, 47.0% of HAIs has led to sepsis in 832 patients. Overall, 57.0% episodes were classified as sepsis, 20.5% as severe sepsis and 22.5% as septic shock. The most common isolated microorganisms from sepsis episodes were Acinetobacter baumannii, Klebsiella pneumoniae and Pseudomonas aeruginosa. The case fatality rate increased with the severity of sepsis and the mean length of ICU-stay was significantly higher in patients with ICU-acquired sepsis than in patients without. Conclusions. Our study provides evidence that ICU-acquired sepsis occurs frequently in Italian ICU patients and is associated with a high case fatality rate and increased length of stay. However, in order to explain these findings further analyses are needed in this population of ICU patients.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-10-31 |