0000000000278376

AUTHOR

Hermann Hinrichs

Time course of human 40 Hz EEG activity accompanying P3 responses in an auditory oddball paradigm

In order to quantify the time course of auditory P3-related gamma activity, root mean square (RMS) values were calculated from band-filtered (30-45 Hz) target and non-target responses in an auditory oddball experiment. Evoked (phase locked) gamma activity was evaluated from the time domain averages, whereas induced (not necessarily phase locked) activity was analyzed on the basis of single trials. Gamma RMS values were integrated across different time windows, namely the prestimulus, N50/P50, N100, pre P3, P3 and post P3 window. The single trial P3 window hereby was defined by a maximum amplitude criterion. In accordance with other studies, we found a pronounced increase of evoked gamma act…

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Alterations of Continuous MEG Measures during Mental Activities

In a pilot study, we investigated the topography of 11 continuous MEG measures for the eyes-opened and eyes-closed condition together with three simple mental tasks (mental arithmetic, visual imagery, word generation). One-minute recordings for each condition from 16 right-handed subjects were analyzed. The electrophysiological measures consisted of 6 spectral band measures together with spectral edge frequency and spectral entropy, plus the time-domain-based entropy of amplitudes (ENA) and the nonlinear measures correlation dimension D2 and Lyapunov exponent L1. In summary, our results indicate a pronounced task-dependent difference between the anterior and the posterior region, but no lat…

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Linear inverse filtering improves spatial separation of nonlinear brain dynamics: a simulation study.

We examined topographic variations in nonlinear measures based on scalp voltages, which were generated by two simulated current dipoles each placed in a different hemisphere of a spherical volume conductor (three-shell model). Dipole dynamics were that of a three-torus and the x-component of the Lorenz-system and scalp voltage were calculated for a configuration of 29 electrode positions. Although estimates for correlation dimension D2 and Lyapunov exponent L1 were close to the theoretical values for the original time series, the simulated scalp voltage data showed almost no topographic resolution of dipole positions. In order to enhance topographic differentiation, we constructed linear in…

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