0000000000283251

AUTHOR

Michaela Harbeck

showing 3 related works from this author

Yersinia pestis DNA from Skeletal Remains from the 6th Century AD Reveals Insights into Justinianic Plague

2013

Yersinia pestis, the etiologic agent of the disease plague, has been implicated in three historical pandemics. These include the third pandemic of the 19th and 20th centuries, during which plague was spread around the world, and the second pandemic of the 14th–17th centuries, which included the infamous epidemic known as the Black Death. Previous studies have confirmed that Y. pestis caused these two more recent pandemics. However, a highly spirited debate still continues as to whether Y. pestis caused the so-called Justinianic Plague of the 6th–8th centuries AD. By analyzing ancient DNA in two independent ancient DNA laboratories, we confirmed unambiguously the presence of Y. pestis DNA in…

MaleHistoryYersinia pestis590Social and Behavioral SciencesPandemicBiology (General)16th CenturyPhylogenyHistory 15th CenturybiologyBacterialHistory 19th Century20th CenturyBiological AnthropologyHistory 16th Century17th CenturyFemaleBase Sequence; Bone and Bones; DNA Bacterial; Female; Genotype; History 15th Century; History 16th Century; History 17th Century; History 19th Century; History 20th Century; History Medieval; Humans; Male; Molecular Sequence Data; Pandemics; Yersinia pestis; Phylogeny; PlagueMedievalResearch ArticleDNA BacterialGenotypeQH301-705.5ImmunologyMolecular Sequence DataPlague (disease)MicrobiologyBone and BonesNOHistory 17th CenturyVirologyGeneticsHumansBase sequenceMolecular BiologyPandemicsBiologyPlague bacillus19th CenturyPlagueBase SequenceDNARC581-607History 20th Centurybiology.organism_classificationVirologyHistory Medieval15th CenturyAncient DNAYersinia pestisAnthropologyYersinia pestis DNAParasitologyImmunologic diseases. Allergy
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Population genomic analysis of elongated skulls reveals extensive female-biased immigration in Early Medieval Bavaria

2018

Significance Many modern European states trace their roots back to a period known as the Migration Period that spans from Late Antiquity to the early Middle Ages. We have conducted the first population-level analysis of people from this era, generating genomic data from 41 graves from archaeological sites in present-day Bavaria in southern Germany mostly dating to around 500 AD. While they are predominantly of northern/central European ancestry, we also find significant evidence for a nonlocal genetic provenance that is highly enriched among resident Early Medieval women, demonstrating artificial skull deformation. We infer that the most likely origin of the majority of these women was sout…

0301 basic medicineHuman MigrationGenetic genealogyPopulationPopulation geneticsMigration PeriodGenetic analysisWhite PeoplePrehistory03 medical and health sciences0302 clinical medicineGermanyHumansEarly MedievalEast AsiaDNA Ancienteducationeducation.field_of_studyMultidisciplinaryPopulation BiologyWhole Genome SequencingGenome HumanGenetic heterogeneitySkullpopulation geneticsGenetic VariationGenomicsBiological Sciencesdemographic inferenceHistory MedievalpaleogenomicsGenetics PopulationPhenotype030104 developmental biologyGeographyArchaeologyHaplotypesEvolutionary biologyGenetic structureFemale030217 neurology & neurosurgeryProceedings of the National Academy of Sciences
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Estimating the chance of success of archaeometric analyses of bone: UV-induced bone fluorescence compared to histological screening

2011

Abstract For most archaeometric analyses on archaeological bone material, such as the determination of the isotopic composition or genetic approaches, an advanced degree of diagenetic alteration can make designated analysis impossible. Since the lack of a positive signal is mostly seen only after time consuming and cost intensive sample processing, the need for an easy-to-apply screening method that allows a pre-selection of samples containing well-preserved biomolecules is obvious. In this study, we visually determined the UV-induced autofluorescence of 76 horse bone cross-sections, all from prehistoric archaeological sites of varying environmental and chronological background. In order to…

Sample (material)Advanced degreeSample processingPaleontologyBiologyOceanographyPredictive valueIsotopic compositionAutofluorescenceBone materialScreening methodEcology Evolution Behavior and SystematicsEarth-Surface ProcessesBiomedical engineeringPalaeogeography, Palaeoclimatology, Palaeoecology
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