0000000000286008

AUTHOR

Cornelia Puskas

showing 2 related works from this author

MERIT Study – “Multicenter Evaluation of Patient- and Lesion-Specific Prognostic Factors for RadioImmunoTherapy with 90yttrium-Labeled Anti-CD20 in F…

2009

Abstract Abstract 4792 Background / Aim Although prognostic factors (PF) for conventional lymphoma therapy are well known and used in clinical practice and medical research, the PF for radioimmunotherapy (RIT) have not been fully defined until now. The aim of this prospective multicenter trial is to identify patient- and lesion-specific PF for a standard RIT using 90Yttrium-labeled anti-CD20-antibodies in relapsed or refractory follicular lymphoma (FL) by means of clinical and image data including FDG-PET and CT. To prove the feasibility of the multicenter web-based data collection and to assess the imaging data we performed an analysis on retrospective data. Material and methods This retro…

medicine.medical_specialtymedicine.medical_treatmentImmunologyStandardized uptake valueBiochemistryLesion03 medical and health sciences0302 clinical medicineMulticenter trialmedicineMedical imagingProspective cohort study030304 developmental biology0303 health sciencesbusiness.industryCell BiologyHematologymedicine.disease3. Good healthLymphomaRadioimmunotherapyRadiologyRefractory Follicular Lymphomamedicine.symptombusiness030215 immunologyBlood
researchProduct

Improved inter-observer agreement of an expert review panel in an oncology treatment trial--Insights from a structured interventional process.

2015

Abstract Purpose Oncologic imaging is a key for successful cancer treatment. While the quality assurance (QA) of image acquisition protocols has already been focussed, QA of reading and reporting offers still room for improvement. The latter was addressed in the context of a prospective multicentre trial on fluoro-deoxyglucose (FDG)–positron-emission tomography (PET)/CT-based chemoradiotherapy for locally advanced non-small cell lung cancer (NSCLC). Material and methods An expert panel was prospectively installed performing blinded reviews of mediastinal NSCLC involvement in FDG–PET/CT. Due to a high initial reporting inter-observer disagreement, the independent data monitoring committee (I…

Cancer Researchmedicine.medical_specialtyLung NeoplasmsContext (language use)Sensitivity and SpecificityDouble-Blind MethodFluorodeoxyglucose F18Carcinoma Non-Small-Cell LungOutcome Assessment Health CaremedicineData monitoring committeeHumansMedical physicsObserver VariationPET-CTmedicine.diagnostic_testbusiness.industryReproducibility of ResultsChemoradiotherapyClinical trialOncologyPositron emission tomographyPositron-Emission TomographyRadiologybusinessTomography X-Ray ComputedQuality assuranceKappaChemoradiotherapyEuropean journal of cancer (Oxford, England : 1990)
researchProduct