0000000000286077

AUTHOR

Nina Pirlich

showing 9 related works from this author

Assessment of haemoglobin measurement by several methods - blood gas analyser, capillary and venous HemoCue® , non-invasive spectrophotometry and lab…

2018

A laboratory haematology analyser is the gold standard for measuring haemoglobin concentration but has disadvantages, especially in neonates. This study compared alternative blood-sparing and non-invasive methods of haemoglobin concentration measurement with the gold standard. Haemoglobin concentrations were measured using a laboratory haematology analyser (reference method), blood gas analyser, HemoCue® using venous and capillary blood samples and a newly developed non-invasive sensor for neonates < 3 kg. A total of 63 measurements were performed. Body weight (2190 (1820-2520 [967-4450]) g) and haemoglobin concentration (12.3 (10.6-15.2 [8.2-20.5]) g.dl-1 ) varied widely. Bias/limits of ag…

Chromatographymedicine.diagnostic_testCapillary actionbusiness.industryAnalyserNon invasiveGold standard (test)Venous blood03 medical and health sciences0302 clinical medicineAnesthesiology and Pain Medicine030202 anesthesiologySpectrophotometrymedicineGas analyser030212 general & internal medicineLaboratory assaybusinessAnaesthesia
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Scalpel cricothyrotomy – with or without speculum: that is the question

2020

medicine.medical_specialtyAnesthesiology and Pain Medicinebusiness.industrymedicine.medical_treatmentGeneral surgeryMedicineCricothyrotomyCritical Care and Intensive Care MedicinebusinessTrends in Anaesthesia and Critical Care
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Non‐invasive haemoglobin measurement as an index test to detect pre‐operative anaemia in elective surgery patients – a prospective study

2020

Non-invasive haemoglobin measurement using absolute values lacks the precision to be the sole basis for the treatment of pre-operative anaemia. However, it can possibly serve as a screening test, indexing 'anaemia' with high sensitivity when values remain under prespecified cut-off values. Based on previous data, non-invasive haemoglobin cut-off values (146 g.l-1 for women and 152 g.l-1 for men) detect true anaemia with 99% sensitivity. An index test with these prespecified cut-off values was verified by prospective measurement of non-invasive and invasive haemoglobin pre-operatively in elective surgical patients. In 809 patients, this showed an estimated sensitivity (95%CI) of 98.9% (94.1-…

AdultMalemedicine.medical_specialtyHaemoglobin levelsSensitivity and SpecificityHemoglobins03 medical and health sciences0302 clinical medicine030202 anesthesiologyInternal medicinePreoperative CareHumansMedicineProspective Studies030212 general & internal medicineElective surgeryProspective cohort studyAgedHematologic Testsbusiness.industryNon invasiveLimits of agreementIndex testAnemiaMiddle AgedPre operativeAnesthesiology and Pain MedicineElective Surgical ProceduresFemalebusinessSurgical patientsAnaesthesia
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Anaesthesia protocol evaluation of the videolaryngoscopy with the McGrath MAC and direct laryngoscopy for tracheal intubation in 1000 patients underg…

2021

IntroductionRapid sequence induction of anaesthesia is indicated in patients with an increased risk of pulmonary aspiration. The main objective of the technique is to reduce the critical time period between loss of airway protective reflexes and rapid inflation of the cuff of the endotracheal tube to minimise the chance of aspiration of gastric contents. The COVID-19 pandemic has reinforced the importance of first-pass intubation success to ensure patient and healthcare worker safety. The aim of this study is to compare the first-pass intubation success rate (FPS) using the videolaryngoscopy compared with conventional direct laryngoscopy in surgical patients with a high risk of pulmonary as…

1682medicine.medical_treatmenteducationLaryngoscopyLaryngoscopeslaw.inventionAnaesthesiasurgeryRandomized controlled triallawIntubation IntratrachealmedicineClinical endpointHumansMulticenter Studies as TopicIntubationAnesthesia1506adult anaesthesiaRapid Sequence Induction and Intubationadult intensive & critical carePandemicsRandomized Controlled Trials as TopicLaryngoscopymedicine.diagnostic_testSARS-CoV-2business.industryTracheal intubationCOVID-19General Medicinemedicine.diseaseRapid sequence inductionPulmonary aspirationAnesthesiaAirway managementbusinessBMJ Open
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A comparison of the Enk Fiberoptic Atomizer Set(™) with boluses of topical anaesthesia for awake fibreoptic intubation.

2016

We compared the Enk Fiberoptic Atomizer Set(™) with boluses of topical anaesthesia administered via the working channel during awake fibreoptic tracheal intubation in 96 patients undergoing elective surgery. Patients who received topical anaesthesia via the atomiser, compared with boluses via the fibreoptic scope, reported a better median (IQR [range]) level of comfort: 1 (1-3 [1-10]) vs. 4 (2-6 [1-10]), p < 0.0001; experienced a reduced total number of coughs: 6 (3-10 [0-34]) vs. 11 (6-13 [0-25]), p = 0.0055; and fewer distinct coughing episodes: 7% vs. 27% respectively, p = 0.0133. The atomiser technique was quicker: 5 (3-6 [2-12]) min vs. 6 (5-7 [2-15]) min, p = 0.0009; and required less…

Malemedicine.medical_specialtymedicine.medical_treatmentFibreoptic intubation03 medical and health sciences0302 clinical medicineBolus (medicine)030202 anesthesiologyIntubation IntratrachealMedicineFiber Optic TechnologyHumansNasal intubationElective surgeryAnesthetics LocalWakefulnessTopical anaesthesiabusiness.industryNebulizers and VaporizersTracheal intubationLidocaine030208 emergency & critical care medicineMiddle AgedSurgeryTopical lidocaineAnesthesiology and Pain MedicineAnesthesiaFemalebusinessAwake intubationAnaesthesia
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Red blood cell transfusion in perioperative pediatric anesthesia: a survey of current practice in Germany.

2018

BACKGROUND Little is known about the current practice of the perioperative transfusion of red blood cells (RBCs) in pediatric patients. This study was performed to evaluate the practice of RBC transfusion in German pediatric anesthesia. STUDY DESIGN AND METHODS An online survey was conducted among members of the German Society of Anesthesiology and Intensive Care. Participants were asked to indicate the hemoglobin (Hb) thresholds for starting RBC transfusion in six cases of different bleeding situations in pediatric anesthesia. Demographics of participants, general knowledge, and application of transfusion rules and guidelines were assessed. RESULTS We included 1207 of 1396 returned questio…

MalePediatricsmedicine.medical_specialtyBlood transfusionAdolescentCritical Caremedicine.medical_treatmentImmunology030204 cardiovascular system & hematology03 medical and health sciencesHemoglobins0302 clinical medicine030202 anesthesiologyInterquartile rangeIntensive careAnesthesiologyGermanySurveys and QuestionnairesImmunology and AllergyMedicineHumansAnesthesiaChildPerioperative Periodbusiness.industryInfant NewbornInfantHematologyGuidelinePerioperativeCurrent practiceFemalePediatric anesthesiabusinessErythrocyte TransfusionTransfusionREFERENCES
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Anaesthetic protocol for paediatric glaucoma examinations: the prospective EyeBIS Study protocol

2021

IntroductionNeonates and young infants with diagnosed or highly suspected glaucoma require an examination under anaesthesia to achieve accurate intraocular pressure (IOP) measurements, since crying or squinting of the eyes may increase IOP and lead to falsely high values. IOP considerably depends on perioperative variables such as haemodynamic factors, anaesthetics, depth of anaesthesia and airway management. The aim of this paper is to report the design and baseline characteristics of EyeBIS, which is a study to develop a standardised anaesthetic protocol for the measurement of IOP under anaesthesia in childhood glaucoma, by investigating the link between the magnitude of IOP and depth of …

Intraocular pressuregenetic structuresmedicine.medical_treatmentGlaucomamedicinepaediatric ophthalmologyHumansGeneral anaesthesia1506Prospective StudiesProspective cohort studyChildIntraocular PressureAnestheticsbusiness.industryanaesthesia in ophthalmologyInfant NewbornRInfantGlaucomaGeneral MedicinePerioperativepaediatric anaesthesiamedicine.diseaseeye diseasesOphthalmologyAnesthesiaBispectral indexMedicineAirway managementPediatric ophthalmologyOcular Hypertensionsense organsbusiness1718BMJ Open
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Airway topical anaesthesia for awake fibreoptic intubation - a reply

2016

Topical anaesthesiamedicine.medical_specialtybusiness.industryFibreoptic intubationSurgery03 medical and health sciences0302 clinical medicineAnesthesiology and Pain Medicine030202 anesthesiologyAnesthesiamedicine030212 general & internal medicinebusinessAirwayAnaesthesia
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Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow

2017

A patient's willingness to cooperate is an absolute precondition for successful awake intubation of the trachea. Whilst drug-sedation of patients can jeopardize their spontaneous breathing, topical anesthesia of the airway is a popular technique. The spray-as-you-go technique represents one of the simplest opportunities to anesthetize the airway mucosa. The application of local anesthetic through the working channel of the flexible endoscope is a widespread practice for anesthetists as well as pulmonologists. There is neither need for additional devices nor special training as a pre-requisite to perform this technique. However, a known clinical problem is the coughing and gagging reflex tha…

medicine.medical_specialtyLidocainemedicine.drug_classmedicine.medical_treatmentGeneral Chemical Engineering030204 cardiovascular system & hematologyGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicinePharyngeal reflexAnesthesiologymedicineIntubation IntratrachealIntubationHumansAnesthetics LocalGeneral Immunology and MicrobiologyLocal anestheticbusiness.industryGeneral NeuroscienceLidocaineEndoscopySurgeryOxygen030220 oncology & carcinogenesisAnesthesiaAnestheticBreathingMedicinebusinessAirwaymedicine.drugAnesthesia Local
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