0000000000289108

AUTHOR

Jesús Lozano Sánchez

showing 3 related works from this author

Agarose/κ-carrageenan-based hydrogel film enriched with natural plant extracts for the treatment of cutaneous wounds.

2020

Abstract Hydrogels for complex and chronic wound dressings must be conformable, absorb and retain wound exudates and maintain hydration. They can incorporate and release bioactive molecules that can accelerate the healing process. Wound dressings have to be in contact with the wound and epidermis, even for long periods, without causing adverse effects. Hydrogel dressing formulations based on biopolymers derived from terrestrial or marine flora can be relatively inexpensive and well tolerated. In the present article hydrogel films composed by agarose (1.0 wt%), κ-carrageenan at three different concentrations (0.5, 1.0 and 1.5 wt%) and glycerol (3.0 wt%) were prepared without recourse to cros…

Chronic woundCell Survival02 engineering and technologyCarrageenanBiochemistryAntioxidants03 medical and health scienceschemistry.chemical_compoundMiceStructural BiologymedicineGlycerolAnimalsFibroblastCytotoxicityMolecular Biology030304 developmental biology0303 health sciencesEpidermis (botany)Plant ExtractsSepharoseGeneral MedicineFibroblasts021001 nanoscience & nanotechnologyMethylgalactosidesBandagesBryopsidaElasticityBiomechanical Phenomenamedicine.anatomical_structureAgarose/κ-carrageenan lend Cryphaea heteromalla bryophyte Wound healingchemistrySelf-healing hydrogelsBiophysicsNIH 3T3 CellsAgaroseSettore CHIM/07 - Fondamenti Chimici Delle Tecnologiemedicine.symptomSwelling0210 nano-technologyInternational journal of biological macromolecules
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Moringa oleifera Leaf Powder as Functional Additive in Cookies to Protect SH-SY5Y Cells

2021

The aim of this work is the evaluation of the addition of Moringa leaf powder (MLP) in cookies in terms of antioxidant properties, dough processability and sensorial properties of the cookies. The total content of biophenols and flavonoids in MLP was detected and the identification of the bioactive molecules was performed by HPLC-ESI-TOF-MS measurements, before and after oven treatment at 180 ◦C for 20 min. After a preliminary evaluation of the MLP water soluble fraction (MLPsf) cytotoxicity, its protective effect against an oxidative injury induced in the SH-SY5Y cells was assessed. Data evidence that the bioactive molecules present in MLPsf are effective in preventing ROS production and i…

TechnologySH-SY5YAntioxidantQH301-705.5QC1-999Bioactive moleculesmedicine.medical_treatmentCytotoxicitymedicine.disease_causeMORINGA OLEIFERA LEAFantioxidant effectsMoringachemistry.chemical_compoundHPLC-ESI-TOF-MS identificationsAntioxidant effects Cytotoxicity HPLC-ESI-TOF-MS identifications Moringa leaf powder Rheologymedicinemoringa leaf powderGeneral Materials ScienceOxidative injuryFood scienceBiology (General)QD1-999InstrumentationFluid Flow and Transfer ProcessesTPhysicsProcess Chemistry and TechnologyGeneral Engineeringfood and beveragesmoringa leaf powder; HPLC-ESI-TOF-MS identifications; cytotoxicity; antioxidant effects; rheology; SEMEngineering (General). Civil engineering (General)Moringa leaf powderComputer Science ApplicationsChemistrychemistryAntioxidant effectsSEMcytotoxicityrheologySettore CHIM/07 - Fondamenti Chimici Delle TecnologieTA1-2040KaempferolRheologyOxidative stress
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Water Extract of Cryphaea heteromalla (Hedw.) D. Mohr Bryophyte as a Natural Powerful Source of Biologically Active Compounds

2019

Bryophytes comprise of the mosses, liverworts, and hornworts. Cryphaea heteromalla, (Hedw.) D. Mohr, is a non-vascular lower plant belonging to mosses group. To the date, the most chemically characterized species belong to the liverworts, while only 3.2% and 8.8% of the species belonging to the mosses and hornworts, respectively, have been investigated. In this work, we present Folin–Ciocalteu and oxygen radical absorbance capacity (ORAC) data related to crude extracts of C. heteromalla obtained by three di erent extraction solvents: pure water (WT), methanol:water (80:20 v/v) (MET), and ethanol:water (80:20 v/v) (ETH). The water extract proved to be the best solvent showing the highest con…

Oxygen radical absorbance capacityBryophytaCoumaric acidMass spectrometryCatalysisArticleInorganic ChemistryExtract HPLC-ESI-TOF-MS analysilcsh:Chemistrychemistry.chemical_compoundCryphaea heteromalla; bryophytes; extract HPLC-ESI-TOF-MS analysis; oxidative stress evaluationMiceCryphaea heteromallabryophytesAnimalsPhysical and Theoretical ChemistryMolecular Biologylcsh:QH301-705.5SpectroscopyExtract HPLC-ESI-TOF-MS analysisChromatographyEthanolChemistryPlant ExtractsOxidative stress evaluationOrganic ChemistryExtraction (chemistry)Bryophytesoxidative stress evaluationGeneral MedicineFree Radical Scavengersextract hplc-esi-tof-ms analysisComputer Science ApplicationsSolventOxidative Stresslcsh:Biology (General)lcsh:QD1-999<i>cryphaea heteromalla</i>BryophyteSettore BIO/03 - Botanica Ambientale E ApplicataNIH 3T3 CellsBryophyteMethanolReactive Oxygen SpeciesInternational Journal of Molecular Sciences
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