A Review of 2000 Years of Paleoclimatic Evidence in the Mediterranean
[EN] The integration of climate information from instrumental data and documentary and natural archives; evidence of past human activity derived from historical, paleoecological, and archaeological records; and new climate modeling techniques promises major breakthroughs for our understanding of climate sensitivity, ecological processes, environmental response, and human impact. In this chapter, we review the availability and potential of instrumental data, less well-known written records, and terrestrial and marine natural proxy archives for climate in the Mediterranean region over the last 2000 years. We highlight the need to integrate these different proxy archives and the importance for…
Longitudinal Study on Sustained Attention to Response Task (SART): Clustering Approach for Mobility and Cognitive Decline
The Sustained Attention to Response Task (SART) is a computer-based go/no-go task to measure neurocognitive function in older adults. However, simplified average features of this complex dataset lead to loss of primary information and fail to express associations between test performance and clinically meaningful outcomes. Here, we combine a novel method to visualise individual trial (raw) information obtained from the SART test in a large population-based study of ageing in Ireland and an automatic clustering technique. We employed a thresholding method, based on the individual trial number of mistakes, to identify poorer SART performances and a fuzzy clusters algorithm to partition the da…
SART and Individual Trial Mistake Thresholds: Predictive Model for Mobility Decline
The Sustained Attention to Response Task (SART) has been used to measure neurocognitive functions in older adults. However, simplified average features of this complex dataset may result in loss of primary information and fail to express associations between test performance and clinically meaningful outcomes. Here, we describe a new method to visualise individual trial (raw) information obtained from the SART test, vis-à-vis age, and groups based on mobility status in a large population-based study of ageing in Ireland. A thresholding method, based on the individual trial number of mistakes, was employed to better visualise poorer SART performances, and was statistically validated with bin…