0000000000294296

AUTHOR

Lars Larsson

A New Systematic Series of Foil Sections with Parallel Sides

Parallel-sided foil sections are used for centerboards and rudders in sailing dinghy classes and also for struts placed in a fluid flow. The objective of this work is to create a systematic series of parallel-sided sections to be used under different conditions, with an emphasis on the sailing dinghies 470, 420 and Optimist. The loss, and surprisingly the gain, in performance relative to 4-digit NACA sections are also investigated. A 2D Reynolds-averaged Navier&ndash

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Hormone replacement therapy improves contractile function and myonuclear organization of single muscle fibres from postmenopausal monozygotic female twin pairs

Ageing is associated with a decline in muscle mass and strength leading to increased physical dependency in old age. Postmenopausal women experience a greater decline than men of similar age in parallel with the decrease in female sex steroid hormone production. We recruited six monozygous female twin pairs (55-59 years old) where only one twin pair was on hormone replacement therapy (HRT use = 7.8 ± 4.3 years) to investigate the association of HRT with the cytoplasmic volume supported by individual myonuclei (myonuclear domain (MND) size,) together with specific force at the single fibre level. HRT use was associated with a significantly smaller (∼27%; P < 0.05) mean MND size in muscle fib…

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Hormone replacement therapy improves contractile function and myonuclear organization of single fibres from postmenopausal monozygotic female twin pairs.

Ageing is associated with a decline in muscle mass and strength leading to increased physical dependency in old age. Postmenopausal women experience a greater decline than men of similar age in parallel with the decrease in female sex steroid hormone production. We recruited six monozygous female twin pairs (55–59 years old) where only one twin pair was on hormone replacement therapy (HRT use = 7.8 ± 4.3 years) to investigate the association of HRT with the cytoplasmic volume supported by individual myonuclei (myonuclear domain (MND) size,) together with specific force at the single fibre level. HRT use was associated with a significantly smaller (∼27%; P < 0.05) mean MND size in muscle fib…

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Effects of combined strength and sprint training on regulation of muscle contraction at the whole-muscle and single-fibre levels in elite master sprinters

The aims of this study were to investigate the mechanisms underlying (1) the ageing-related motor handicap at the whole muscle, cellular, contractile protein and myonuclear levels; and (2) ageing-related differences in muscle adaptability.In vivo muscles function was studied in the knee extensors. Decreases were observed in isokinetic and isometric torque outputs in old age in the sedentary men and women and elite master sprinters. A 20-week long specific sprint and resistance training successfully improved the maximal isometric force and rate of force development in a subgroup of master sprinters.In vitro measurements were performed in muscle biopsies from the vastus lateralis muscle. Immu…

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New Aspects of the Mesolithic-Neolithic Cemeteries and Settlement at Zvejnieki, Northern Latvia

The paper reflects upon recent international research at Zvejnieki in northern Latvia, a renowned complex of a burial ground and two settlement sites used in the Mesolithic and Neolithic. Since its discovery and first excavations in the 1960s, Zvejnieki continues to produce evidence that provides new grounds for understanding mortuary practises and ancient lifeways. This information is relevant for other contemporary sites in Europe revealing new and hitherto unexpected elements of burial traditions. It is suggested that the Zvejnieki population was partly mobile, and the site was one of the places to bury the dead. The ancestral link was established through transportation and use of occupa…

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Aging, muscle fiber type, and contractile function in sprint-trained athletes

Biopsy samples were taken from the vastus lateralis of 18- to 84-yr-old male sprinters ( n = 91). Fiber-type distribution, cross-sectional area, and myosin heavy chain (MHC) isoform content were identified using ATPase histochemistry and SDS-PAGE. Specific tension and maximum shortening velocity ( Vo) were determined in 144 single skinned fibers from younger (18–33 yr, n = 8) and older (53–77 yr, n = 9) runners. Force-time characteristics of the knee extensors were determined by using isometric contraction. The cross-sectional area of type I fibers was unchanged with age, whereas that of type II fibers was reduced ( P &lt; 0.001). With age there was an increased MHC I ( P &lt; 0.01) and re…

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Paltamo

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