0000000000295277

AUTHOR

L. Gray

showing 4 related works from this author

Observation of high-energy neutrinos using Cerenkov detectors embedded deep in Antarctic ice.

2001

Neutrinos are elementary particles that carry no electric charge and have little mass. As they interact only weakly with other particles, they can penetrate enormous amounts of matter, and therefore have the potential to directly convey astrophysical information from the edge of the Universe and from deep inside the most cataclysmic high-energy regions. The neutrino's great penetrating power, however, also makes this particle difficult to detect. Underground detectors have observed low-energy neutrinos from the Sun and a nearby supernova2, as well as neutrinos generated in the Earth's atmosphere. But the very low fluxes of high-energy neutrinos from cosmic sources can be observed only by mu…

PhysicsAntarctic Muon And Neutrino Detector ArrayMultidisciplinaryPhysics::Instrumentation and DetectorsAstrophysics::High Energy Astrophysical PhenomenaSolar neutrinoAstronomyAstrophysicsSolar neutrino problemCosmic neutrino backgroundNeutrino detectorMeasurements of neutrino speedHigh Energy Physics::ExperimentNeutrinoNeutrino astronomyNature
researchProduct

RECENT RESULTS FROM AMANDA

2001

We present results based on data taken in 1997 with the 302-PMT Antarctic Muon and Neutrino Detector Array-B10 ("AMANDA-B10") array. Atmospheric neutrinos created in the northern hemisphere are observed indirectly through their charged current interactions which produce relativistic, Cherenkov-light-emitting upgoing muons in the South Pole ice cap. The reconstructed angular distribution of these events is in good agreement with expectation and demonstrates the viability of this ice-based device as a neutrino telescope.

PhysicsNuclear and High Energy PhysicsMuonPhysics::Instrumentation and DetectorsAstrophysics::High Energy Astrophysical PhenomenaSolar neutrinoAstrophysics::Instrumentation and Methods for AstrophysicsAstronomyAstronomy and AstrophysicsAstrophysicsSolar neutrino problemAtomic and Molecular Physics and OpticsNeutrino detectorMeasurements of neutrino speedHigh Energy Physics::ExperimentNeutrinoNeutrino oscillationPhysics::Atmospheric and Oceanic PhysicsCharged currentInternational Journal of Modern Physics A
researchProduct

TH-302 + Gemcitabine (G + T) vs Gemcitabine (G) in Patients with Previously Untreated advanced Pancreatic Cancer (PAC)

2012

ABSTRACT Background TH-302 is a hypoxia targeted prodrug with a hypoxia-triggered 2-nitroimidazole component designed to release the DNA alkylator, bromo-isophosphoramide mustard (Br-IPM), when reduced in severe hypoxia. A randomized Phase 2B study (NCT01144455) was conducted to assess the benefit of G + T to standard dose G as first-line therapy of PAC. Materials and methods An open-label multi-center study of two dose levels of TH-302 (240 mg/m2 or 340 mg/m2) in combination with G versus G alone (randomized 1:1:1). G (1000 mg/m2) and T were administered IV over 30-60 minutes on Days 1, 8 and 15 of a 28-day cycle. Patients on the G could crossover after progression and be randomized to a G…

medicine.medical_specialtyGastrointestinal tumorsPerformance statusbusiness.industryHematologySevere hypoxiaNeutropeniamedicine.diseaseRashGastroenterologyDiscontinuationNon colorectalOncologyInternal medicineToxicitymedicinemedicine.symptombusinessAnnals of Oncology
researchProduct

Measurement of thett¯production cross section inpp¯collisions ats=1.96  TeVusing soft electronb-tagging

2010

The authors present a measurement of the t{bar t} production cross section using events with one charged lepton and jets from p{bar p} collisions at a center-of-mass energy of 1.96 TeV. A b-tagging algorithm based on the probability of displaced tracks coming from the event interaction vertex is applied to identify b quarks from top decay. Using 318 pb{sup -1} of data collected with the CDF II detector, they measure the t{bar t} production cross section in events with at least one restrictive (tight) b-tagged jet and obtain 8.9{sub -1.0}{sup +1.0}(stat.){sub -1.0}{sup +1.1}(syst.) pb. The cross section value assumes a top quark mass of m{sub t} is presented in the paper. This result is cons…

Top quarkCollider physicsHadronTevatronGeneral Physics and AstronomyElementary particleKinematicsElectronJet (particle physics)01 natural sciences7. Clean energyParticle identificationlaw.inventionlawInvariant massFermilabNuclear ExperimentQuantum chromodynamicsPhysicsLarge Hadron ColliderLuminosity (scattering theory)Supersymmetryb-taggingHadronizationTransverse planeProduction (computer science)Collider Detector at FermilabQuarkSemileptonic decayNuclear and High Energy PhysicsParticle physicsBar (music)Astrophysics::High Energy Astrophysical PhenomenaBottom quarkMeasure (mathematics)Standard ModelNuclear physicsCross section (physics)Particle decay0103 physical sciencesCollider010306 general physicsCompact Muon SolenoidMuonBranching fraction010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyMultiplicity (mathematics)FermionVertex (geometry)Pair productionHigh Energy Physics::ExperimentEnergy (signal processing)Bar (unit)LeptonPhysical Review D
researchProduct