0000000000298452

AUTHOR

Anselmo Caricato

showing 4 related works from this author

Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study

2021

Background: To date, 750 000 patients with COVID-19 worldwide have required mechanical ventilation and thus are at high risk of acute brain dysfunction (coma and delirium). We aimed to investigate the prevalence of delirium and coma, and risk factors for delirium in critically ill patients with COVID-19, to aid the development of strategies to mitigate delirium and associated sequelae. Methods: This multicentre cohort study included 69 adult intensive care units (ICUs), across 14 countries. We included all patients (aged ≥18 years) admitted to participating ICUs with severe acute respiratory syndrome coronavirus 2 infection before April 28, 2020. Patients who were moribund or had life-suppo…

Pulmonary and Respiratory Medicinemedicine.medical_specialtymedicine.medical_treatmentcovid-19; deliriumOutcomesLower riskCritical IlnessTask-Force03 medical and health sciences0302 clinical medicinedeliriumSDG 3 - Good Health and Well-beingIntensive-Care-UnitIntensive careSettore MED/41 - ANESTESIOLOGIAmedicineSurvivors030212 general & internal medicineSimplified Acute Physiology ScoreMechaniically Ventilated PatientsEpitiomologyMechanical ventilationComaIntensive-Care-Unit Mechaniically Ventilated Patients Clinical practice Guidelines Critical Ilness Task-Force Sedation ICU Survivors Outcomes Epitiomologybusiness.industrycovidRetrospective cohort studyArticlesClinical practice Guidelinescovid delirium030228 respiratory systemcovid-19SedationICUEmergency medicineDeliriummedicine.symptombusinessCohort studyThe Lancet. Respiratory Medicine
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Intracranial pressure monitoring in patients with acute brain injury in the intensive care unit (SYNAPSE-ICU): an international, prospective observat…

2021

Background: The indications for intracranial pressure (ICP) monitoring in patients with acute brain injury and the effects of ICP on patients’ outcomes are uncertain. The aims of this study were to describe current ICP monitoring practises for patients with acute brain injury at centres around the world and to assess variations in indications for ICP monitoring and interventions, and their association with long-term patient outcomes. Methods: We did a prospective, observational cohort study at 146 intensive care units (ICUs) in 42 countries. We assessed for eligibility all patients aged 18 years or older who were admitted to the ICU with either acute brain injury due to primary haemorrhagic…

MaleIntracranial PressureGlasgow Outcome ScaleMalalties cerebralsintensive care unitlaw.inventionCohort Studies0302 clinical medicinelawBrain Injuries TraumaticMedicineacute brain injuryProspective StudiesProspective cohort studyUnitats de cures intensivesIntracranial pressureIntensive care unitsGlasgow Outcome ScaleMiddle AgedIntensive care unitIntensive Care UnitsHypertensionIntracranial pressure monitoringFemaleHipertensióBrain diseasesAdultmedicine.medical_specialtyCritical CareTraumatic brain injuryIntracranial pressure monitoring brain injury03 medical and health sciencesInternal medicineIntensive careSettore MED/41 - ANESTESIOLOGIAHumansGlasgow Coma ScaleAgedMonitoring Physiologicbusiness.industryGlasgow Coma Scale030208 emergency & critical care medicineICPIntracranial pressure monitoringmedicine.diseaseBrain InjuriesNeurology (clinical)Intracranial Hypertensionbusiness030217 neurology & neurosurgery
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Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure : the DIANA study

2020

© 2020 The Author(s).

OriginalDELPHI METHODCritical Care and Intensive Care MedicineGUIDELINESlaw.invention0302 clinical medicineAnti-Infective Agents[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseaseslawEpidemiologyMedicine and Health SciencesAntimicrobial de-escalationEPIDEMIOLOGYComputingMilieux_MISCELLANEOUS[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseasesVentilator-associated pneumoniaIntensive care unitAnti-Bacterial Agents3. Good healthIntensive Care UnitsSTEWARDSHIP PROGRAM[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/VirologyCohortAntimicrobial de-escalation; Bacterial infection; Clinical cure; Empirical therapy; Intensive care unit;Clinical cureAntimicrobial de-escalation; Bacterial infection; Clinical cure; Empirical therapy; Intensive care unitAdultmedicine.medical_specialtyCombination therapyCritical IllnessANTIBIOTIC-THERAPYNO03 medical and health sciences[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemBETA-LACTAMInternal medicineSettore MED/41 - ANESTESIOLOGIAmedicineHumans[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyIntensive care unitVENTILATOR-ASSOCIATED PNEUMONIAbusiness.industrySEPTIC SHOCKR-PACKAGEbacterial infectionIntensive care unit.030208 emergency & critical care medicinemedicine.disease[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/BacteriologyEmpirical therapyDiscontinuationSEVERE SEPSISlnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]Carbapenems030228 respiratory systemRelative riskBacterial infectionbusinessDe-escalation
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Treatments for intracranial hypertension in acute brain-injured patients: grading, timing, and association with outcome. Data from the SYNAPSE-ICU st…

2023

Purpose: Uncertainties remain about the safety and efficacy of therapies for managing intracranial hypertension in acute brain injured (ABI) patients. This study aims to describe the therapeutical approaches used in ABI, with/without intracranial pressure (ICP) monitoring, among different pathologies and across different countries, and their association with six months mortality and neurological outcome. Methods: A preplanned subanalysis of the SYNAPSE-ICU study, a multicentre, prospective, international, observational cohort study, describing the ICP treatment, graded according to Therapy Intensity Level (TIL) scale, in patients with ABI during the first week of intensive care unit (ICU) a…

Subarachnoid haemorrhageTraumatic brain injuryIntracranial pressureTherapy intensity levelCritical Care and Intensive Care MedicineIntracranial haemorrhageIntensive Care Medicine
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