0000000000298516

AUTHOR

Jacques Creteur

showing 3 related works from this author

Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study

2021

Background: To date, 750 000 patients with COVID-19 worldwide have required mechanical ventilation and thus are at high risk of acute brain dysfunction (coma and delirium). We aimed to investigate the prevalence of delirium and coma, and risk factors for delirium in critically ill patients with COVID-19, to aid the development of strategies to mitigate delirium and associated sequelae. Methods: This multicentre cohort study included 69 adult intensive care units (ICUs), across 14 countries. We included all patients (aged ≥18 years) admitted to participating ICUs with severe acute respiratory syndrome coronavirus 2 infection before April 28, 2020. Patients who were moribund or had life-suppo…

Pulmonary and Respiratory Medicinemedicine.medical_specialtymedicine.medical_treatmentcovid-19; deliriumOutcomesLower riskCritical IlnessTask-Force03 medical and health sciences0302 clinical medicinedeliriumSDG 3 - Good Health and Well-beingIntensive-Care-UnitIntensive careSettore MED/41 - ANESTESIOLOGIAmedicineSurvivors030212 general & internal medicineSimplified Acute Physiology ScoreMechaniically Ventilated PatientsEpitiomologyMechanical ventilationComaIntensive-Care-Unit Mechaniically Ventilated Patients Clinical practice Guidelines Critical Ilness Task-Force Sedation ICU Survivors Outcomes Epitiomologybusiness.industrycovidRetrospective cohort studyArticlesClinical practice Guidelinescovid delirium030228 respiratory systemcovid-19SedationICUEmergency medicineDeliriummedicine.symptombusinessCohort studyThe Lancet. Respiratory Medicine
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Cerebrospinal Fluid Glucose and Lactate Levels After Subarachnoid Hemorrhage: A Multicenter Retrospective Study.

2019

BACKGROUND In patients with subarachnoid hemorrhage (SAH), abnormalities in glucose and lactate metabolism have been described using cerebral microdialysis. Glucose and lactate concentrations in cerebrospinal fluid (CSF) are more easily accessible, but scarce data are available in this setting. The aim of this study is to assess the relationship of CSF glucose and lactate with blood concentrations and with unfavorable neurological outcome after SAH. METHODS A retrospective cohort study was conducted in 5 European University intensive care units. Patients aged 18 years and above who were admitted after a nontraumatic SAH over a 4-year period (2011 to 2014) were included if they had an extern…

Blood GlucoseMaleSubarachnoid hemorrhageCSF glucoseCohort Studies03 medical and health sciences0302 clinical medicineCerebrospinal fluid030202 anesthesiologyIntensive careMedicineHumansLactic AcidAgedRetrospective Studiesbusiness.industryGlasgow Outcome ScaleGlasgow Coma ScaleBrainMiddle AgedSubarachnoid Hemorrhagemedicine.diseaseAnesthesiology and Pain MedicineGlucoseAnesthesiaArterial bloodSurgeryFemaleNeurology (clinical)business030217 neurology & neurosurgeryExternal ventricular drainJournal of neurosurgical anesthesiology
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Hyperventilation in Adult TBI Patients: How to Approach It?

2021

Hyperventilation is a commonly used therapy to treat intracranial hypertension (ICTH) in traumatic brain injury patients (TBI). Hyperventilation promotes hypocapnia, which causes vasoconstriction in the cerebral arterioles and thus reduces cerebral blood flow and, to a lesser extent, cerebral blood volume effectively, decreasing temporarily intracranial pressure. However, hyperventilation can have serious systemic and cerebral deleterious effects, such as ventilator-induced lung injury or cerebral ischemia. The routine use of this therapy is therefore not recommended. Conversely, in specific conditions, such as refractory ICHT and imminent brain herniation, it can be an effective life-savin…

Traumatic brain injurybusiness.industrytraumatic brain injuryIschemiahyperventilationReviewLung injurymedicine.diseaseBrain herniationcerebral ischemialcsh:RC346-429hypocapniaHypocapniaCerebral blood flowNeurologyAnesthesiaintracranial hypertensionHyperventilationmedicineNeurology (clinical)medicine.symptombusinesslcsh:Neurology. Diseases of the nervous systemIntracranial pressureFrontiers in neurology
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