0000000000299571
AUTHOR
Fouad Mellouki
Diterpenoids from Tetraclinis articulata that Inhibit Various Human Leukocyte Functions
Ten new compounds, eight of them pimarane derivatives (1-8), together with a menthane dimer (9) and a totarane diterpenoid (10), were isolated from the leaves and wood of Tetraclinis articulata. The structures of 1-10 were established by using spectroscopic techniques, including 2D NMR spectra. Pimaranes 1-5 were found to possess an unusual cis interannular union of the B and C rings, which, from a biogenetic perspective, could be derived from the hydration of a carbocation at C-8. Compounds 4-6 and a mixture of 7 and 11 modulated different human leukocyte functions at a concentration of 10 microM, mainly the degranulation process measured as myeloperoxidase release and, to a lesser extent,…
Composition and Antimicrobial Activity of Essential Oil ofAnthemis tenuisectaBall
Abstract The Chemical composition of the essential oil of Anthemis tenuisecta Ball. (Anthemideae) was analyzed by gas Chromatography-mass spectrometry (GC-MS). Forty eight components accounting for 89.5 % of the oil were identified, being camphor (17.5 %), 6-methyl-5-hepten-2-one (17.1 %), borneol (11.5 %), sesquicineole (11%) and camphene (5.7 %) the main compounds. In the antibacterial diffusion assay, the oil showed activity against Gram-positive bacteria.
Chemical Composition of the Essential Oils ofPistacia atlanticaDesf.
The chemical composition of the three essential oils obtained by hydrodistillation of the resin, leaves and fruits of Pistacia atlantica Desf. (Anacardiaceae) was studied by GC and GC/MS. Monoterpene hydrocarbons constituted the main chemical group in the resin oil, with α-pinene (42.9%) and β-pinene (13.2%) as the major components. Oil of the fruits contained high amounts of oxygenated monoterpenes, with bornyl acetate (21.5%) as the major component, while oxygenated monoterpenes and sesquiterpenes were found to predominate in the oil of leaves among which terpinen-4-ol (21.7%) and elemol (20.0%) were the most abundant components.
Composition and Antibacterial Activity of Essential Oils ofCladanthus arabicusCass. (Asteraceae)
Abstract The chemical composition of the essential oils of the aerial parts (stems and leaves: sample A) and flowers (sample B) of Cladanthus arabicus Cass., were analysed by GC-MS. Monoterpenes hydrocarbons constituted the main chemical group in both essential oils, with Sabinene, β-pinene, α-pinene, myrcene, α-phellandrene and p-cymene as the main compounds. Sample A was tested for its antimicrobial activity against six Gram positive and negative bacteria. Results showed that the oil exhibited a significant antibacterial activity.
In vitro antibacterial and biofilm inhibitory activity of the sawdust essential oil of Tetraclinis articulata (vahl) against catheter-associated Staphylococcus aureus clinical isolates
Abstract The aim of the present study was to determine the chemical composition, antibacterial and antibiofilm activities of the essential oil of sawdust from root burl wood of T. articulata. Nine strains including 8 clinical isolates from catheters-related infections and one ATCC 25923 were tested. Twenty-seven different compounds were identified by GC–MS in the essential oil of T. articulata extracted by hydrodistillation. Carvacrol and cedrol were the principal compounds representing 34.37 ± 0.07 and 11.07 ± 0.09 respectively. The EO had a strong antibacterial activity against all strains including one Multidrug-Resistant (MDR) and two Methicillin-Resistant S. aureus strains. Inhibition …
Chemical composition and antibacterial activity of essential oil of Pulicaria odora L.
The chemical composition of the volatile oil constituent from Pulicaria odora L. roots has been analyzed by GC/MS. Twenty-seven components were identified, being thymol (47.83%) and its derivative isobutyrate (30.05%) the main constituents in the oil. Furthermore, the oil was tested against seven bacteria at different concentrations. Results showed that the oil exhibited a significant antibacterial activity.