0000000000302394
AUTHOR
B. Chaillot
Formation des agrégats à partir d'une phase cristalline d'acide orthoborique. Intérêt pour la technologie des poudres pharmaceutiques
National audience
Etude de la morphologie de l'interface reactive de dissolution en utilisant le concept de géométrie fractale
National audience
Influence of the parameters molecular structure and granularity on the compactibility of a powder
Drug Dev. Ind. Pharm. ISI Document Delivery No.: RP128 Times Cited: 3 Cited Reference Count: 14 Andres, c ndiaye, a thomas, c tromelin, a chaillot, b pourcelot, y; International audience; The aim of this study was to determine whether it is possible to obtain better characterization of materials in order to find out if these one are suitable in Quality Assurance for direct tableting. We tried to show that a methodological approach combining chemical, physical and technological aspects could control the direct compression process. We chose orthoboric acid as a study model for the direct compression. From a chemical point of view, our findings show only one crystalline molecular structure (RX…
Aptitude à la comprimabilité : structure moléculaire - état particulaire
International audience
Relationship between particle size and dissolution rate of bulk powders and sieving characterized fractions of two qualities of orthoboric acid
Drug Dev. Ind. Pharm. ISI Document Delivery No.: VN279 Times Cited: 1 Cited Reference Count: 22 Tromelin, A Habillon, S Andres, C Pourcelot, Y Chaillot, B; International audience; We have carried out a study of the particle size distribution and aqueous dissolution rate of two commercially available qualities of orthoboric acid, labeled ''crystal'' (ABC) and ''powder'' (ABP). In a previous work, we have shown that the two commercial qualities of orthoboric acid chosen as model compound (''powder'' and ''crystal'') are related to the same crystal network in spite of their different names. However, these two qualities have very different size particle distributions, as previously determined b…