0000000000304053
AUTHOR
Antonio Baldi
Recurrent Ischemic Stroke and Bleeding in Patients With Atrial Fibrillation Who Suffered an Acute Stroke While on Treatment With Nonvitamin K Antagonist Oral Anticoagulants: The RENO-EXTEND Study.
Background: In patients with atrial fibrillation who suffered an ischemic stroke while on treatment with nonvitamin K antagonist oral anticoagulants, rates and determinants of recurrent ischemic events and major bleedings remain uncertain. Methods: This prospective multicenter observational study aimed to estimate the rates of ischemic and bleeding events and their determinants in the follow-up of consecutive patients with atrial fibrillation who suffered an acute cerebrovascular ischemic event while on nonvitamin K antagonist oral anticoagulant treatment. Afterwards, we compared the estimated risks of ischemic and bleeding events between the patients in whom anticoagulant therapy was chan…
Reduced Admissions for Cerebrovascular Events during COVID-19 Outbreak in Italy
Supplemental Digital Content is available in the text.
Novel constant current driver for ISFET/MEMFETs characterization
Abstract In the present work a new constant current driver for ISFETs and MEMFETs sensors has been developed. The proposed circuit maintains the ISFET/MEMFET operation point at constant drain–source current and voltage. The combination of some programmable current sources and an appropriate selection of a simple precision resistor allow a good ISFET/MEMFET polarization. The use of operational amplifiers with low offset and drift are required to provide the buffering function needed by the sensor.
Novel voltage-controlled conditioning circuit applied to the ISFETs temporary drift and thermal dependency
This paper describes a novel conditioning circuit applied to ion-sensitive field-effect transistors/membrane-ion-sensitive field-effect transistors (ISFETs/MEMFETs) sensors. The novel conditioning circuit allows the sensor polarization with the needed either voltage or current required in each application, thanks to two completely independent voltage-controlled blocks (current and voltage blocks). The control of the voltage block is the most critical point in our design because the voltage block maintains the sensor feedback stable, avoiding the thermal and temporary drifts of the sensor feedback.
Risk Factors for Intracerebral Hemorrhage in Patients With Atrial Fibrillation on Non–Vitamin K Antagonist Oral Anticoagulants for Stroke Prevention
Background and Purpose: Clinical trials on stroke prevention in patients with atrial fibrillation have consistently shown clinical benefit from either warfarin or non–vitamin K antagonist oral anticoagulants (NOACs). NOAC-treated patients have consistently reported to be at lower risk for intracerebral hemorrhage (ICH) than warfarin-treated patients. The aims of this prospective, multicenter, multinational, unmatched, case-control study were (1) to investigate for risk factors that could predict ICH occurring in patients with atrial fibrillation during NOAC treatment and (2) to evaluate the role of CHA 2 DS 2 -VASc and HAS-BLED scores in the same setting. Methods: Cases were consecutive pa…