0000000000304239

AUTHOR

Keith B. Isaacson

showing 2 related works from this author

The extent of adhesion induction through electrocoagulation and suturing in an experimental rat study.

2008

Objective To investigate the effect of three types of peritoneal trauma occurring during surgery (high-frequency bipolar current, suturing, and mechanical damage) on postoperative adhesion formation in a rodent animal model. Design Randomized, controlled experimental trial in an in vitro animal model. Setting Laboratory facilities of a university department of obstetrics and gynecology. Animal(s) Thirty-five female Wistar rats. Intervention(s) Bilateral experimental lesions were created on the abdominal wall in every animal. The effect of minimal electrocoagulation was examined by creating lesions (n = 14) through sweeps of a bipolar forceps with a duration of 1 second and standardized pres…

medicine.medical_specialtymedicine.medical_treatmentAdhesion (medicine)Tissue AdhesionsElectrocoagulationBipolar forcepsAbdominal wallAnimal modelPeritoneumElectrocoagulationMedicineAnimalsRats Wistarbusiness.industryParietal peritoneumAbdominal WallSuture TechniquesObstetrics and GynecologyPostoperative adhesionmedicine.diseaseSurgeryRatsDisease Models Animalmedicine.anatomical_structureReproductive MedicineFemalebusinessFertility and sterility
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A pilot study of laparoscopic adhesion prophylaxis after myomectomy with a copolymer designed for endoscopic application.

2009

Abstract Study Objective To assess the laparoscopic handling and safety of D,L-polylactide-e-caprolactone-trimethylene carbonate (PCT) copolymer after myomectomy and compare it with icodextrin. In contrast to previously developed solid barriers, the material has rationally designed properties that are advantageous for convenient laparoscopic application. Design A randomized, single-blinded clinical study (Canadian Task Force Classification I). Setting Single-center study in a German University Hospital. Patients Thirty patients who underwent laparoscopic myomectomy were enrolled. Interventions After laparoscopic myomectomy and subsequent reconstruction of the uterus with interrupted sutures…

Adultmedicine.medical_specialtyRandomizationPolyestersAdhesion (medicine)Pilot ProjectsTissue AdhesionsPeritoneal DiseasesIcodextrinIcodextrinmedicineHumansSingle-Blind MethodAdverse effectLaparoscopyGlucansmedicine.diagnostic_testLeiomyomabusiness.industryPelvic painSuture TechniquesObstetrics and GynecologyAdhesion barriermedicine.diseaseSurgerymedicine.anatomical_structureGlucoseTreatment OutcomeUterine NeoplasmsAbdomenFemaleLaparoscopymedicine.symptombusinessFollow-Up StudiesJournal of minimally invasive gynecology
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