0000000000305342

AUTHOR

Nils-halvdan Morken

Obstetric and Neonatal Outcome of Pregnancies Fathered by Males on Immunosuppression After Solid Organ Transplantation

Immunosuppressive drugs may influence spermatogenesis, but little is known about outcome of pregnancies fathered by transplanted males. We estimated risk of adverse outcomes in pregnancies (with data after the first trimester) fathered by males that had undergone organ transplantation and were treated with immunosuppression. A population-based study, linking data from the Norwegian transplant registry and the Medical Birth Registry of Norway during 1967-2009 was designed. All Norwegian men undergoing solid organ transplantation were included. Odds ratios for major malformations, preeclampsia, preterm delivery (<37 weeks) and small-for-gestational-age were obtained using logistic regression.…

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722: Maternal solid organ transplantation and pregnancy outcome; a national population-based cohort study

outcome; a national population-based cohort study Nils-Halvdan Morken, Cesar Diaz-Garcia, Mats Brannstrom University of Bergen, Public Health and Primary Health care, Bergen, Norway, University of Valencia, Gynecology and Obstetrics, Valencia, Spain, University of Gothenburg, Obstetrics and Gynecology, Valencia, Sweden OBJECTIVE: The first pregnancy with a live birth after solid organ transplantation in the human occurred more than 50 years ago. Still, knowledge about this very special patient group is limited. The objective was to assess the risk of adverse pregnancy outcome after transplant compared to pregnancies before transplant in females. We also compared the risk after transplant wi…

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