0000000000305656

AUTHOR

Slim Ben Jemaa

showing 4 related works from this author

Genome-wide detection of signatures of selection in three Valdostana cattle populations

2020

International audience; The Valdostana is a local dual purpose cattle breed developed in Italy. Three populations are recognized within this breed, based on coat colour, production level, morphology and temperament: Valdostana Red Pied (VPR), Valdostana Black Pied (VPN) and Valdostana Chestnut (VCA). Here, we investigated putative genomic regions under selection among these three populations using the Bovine 50K SNP array by combining three different statistical methods based either on allele frequencies (F-ST) or extended haplotype homozygosity (iHS and Rsb). In total, 8, 5 and 8 chromosomes harbouring 13, 13 and 16 genomic regions potentially under selection were identified by at least tw…

CoatCandidate geneMeatGenotypelocal cattle population[SDV]Life Sciences [q-bio]Quantitative Trait LociBovine BeadChip 50K; candidate genes; local cattle populations; selection signaturesRuns of HomozygosityBiologyBreedingGenomePolymorphism Single Nucleotideselection signatures03 medical and health sciencesFood AnimalsGene FrequencyAnimalsSelection GeneticGeneAllele frequencySelection (genetic algorithm)Genetic Association Studies030304 developmental biology2. Zero hungerGenetics0303 health sciencesGenomeBehavior AnimalHomozygote0402 animal and dairy sciencecandidate geneBovine BeadChip 50K04 agricultural and veterinary sciencesGeneral Medicine040201 dairy & animal sciencelocal cattle populationsMilkPhenotypeHaplotypesAnimal Science and ZoologyCattlecandidate genesSNP array
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Genomic characterization of Algerian Guelmoise cattle and their genetic relationship with other North African populations inferred from SNP genotypin…

2018

International audience; Understanding between and within-breeds genetic variability is essential in the choice of conservation management decisions for threatened populations. In this study we assessed the genetic diversity of the Algerian Guelmoise cattle (GUE) by analyzing data on 24 GUE individuals genotyped for the Illumina BovineSNP50 BeadChipv2. We also provided a detailed description of the population structure of GUE using comparisons with 23 worldwide cattle populations, selected as being representative of African, South European and indicine populations, in addition to four North African populations. We show that GUE is an admixed population which has strong genetic similarity to …

0301 basic medicine[SDV]Life Sciences [q-bio]PopulationSNPGenetic relationshipBiologyRuns of homozygosityGene flow03 medical and health sciencesAlgerian cattlePhylogeneticSettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoGenetic variabilityeducationsnps2. Zero hunger[SDV.GEN]Life Sciences [q-bio]/Geneticseducation.field_of_studyGenetic diversityGeneral VeterinaryPhylogenetic tree0402 animal and dairy science04 agricultural and veterinary sciences040201 dairy & animal scienceSNP genotypingphylogenetics[SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics030104 developmental biologyEvolutionary biologyVeterinary (all)Animal Science and ZoologyGenetic structureInbreeding
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Combined approaches to identify genomic regions involved in phenotypic differentiation between low divergent breeds: Application in Sardinian sheep p…

2019

Selective breeding has led to modifications in the genome of many livestock breeds. In this study, we identified the genomic regions that may explain some of the phenotypic differences between two closely related breeds from Sardinia. A total of 44 animals, 20 Sardinian Ancestral Black (SAB) and 24 Sardinian White (SW), were genotyped using the Illumina Ovine 50K array. A total of 68, 38 and 15 significant markers were identified using the case–control genome-wide association study (GWAS), the Bayesian population differentiation analysis (FST) and the Rsb metric, respectively. Comparisons among the approaches revealed a total of 22 overlapping markers between GWAS and FST and one marker bet…

CoatGenotypePopulationGenome-wide association studygenome-wide methodsBiologySelective breedingGenomePolymorphism Single NucleotideSettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoFood Animalsgenome-wide methods; genomic regions; Ovine BeadChip50K; Sardinian sheep breedsSardinian sheep breedsAnimalsGenetic variabilitygenomic regionseducationGeneOvine BeadChip50Keducation.field_of_studySheepHomozygoteMolecular Sequence AnnotationGeneral MedicineGenomicsgenome-wide methodgenomic regionWhite (mutation)PhenotypeEvolutionary biologyAnimal Science and ZoologyJournal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und ZuchtungsbiologieREFERENCES
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Refining the genetic structure and relationships of European cattle breeds through meta-analysis of worldwide genomic SNP data, focusing on Italian c…

2020

AbstractThe availability of genotyping assays has allowed the detailed evaluation of cattle genetic diversity worldwide. However, these comprehensive studies did not include some local European populations, including autochthonous Italian cattle. In this study, we assembled a large-scale, genome-wide dataset of single nucleotide polymorphisms scored in 3,283 individuals from 205 cattle populations worldwide to assess genome-wide autozygosity and understand better the genetic relationships among these populations. We prioritized European cattle, with a special focus on Italian breeds. Moderate differences in estimates of molecular inbreeding calculated from runs of homozygosity (FROH) were o…

0301 basic medicineBoviniGenotypePopulation geneticslcsh:MedicineGenome-wide association studyBiologyRuns of HomozygosityBiodiversità zootecnicaPolymorphism Single NucleotideBiodiversità zootecnica bovini miglioramento geneticoArticleLinkage DisequilibriumSettore AGR/17 - Zootecnica Generale E Miglioramento Genetico03 medical and health sciences0302 clinical medicineMeta-Analysis as TopicAnimalsInbreedingDomesticationlcsh:ScienceGenotypingPhylogenyAnimal breedingGenetic diversityboviniMultidisciplinarylcsh:RHomozygotebiology.organism_classificationCattle breeds genetic diversity SNPs.Europe030104 developmental biologyItalyEvolutionary biologyGenetic structuremiglioramento geneticolcsh:QCattleInbreeding030217 neurology & neurosurgeryGenome-Wide Association StudyScientific Reports
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