Endurance training damages small airway epithelium in mice.

RATIONALE: In athletes, airway inflammatory cells were found to be increased in induced sputum or bronchial biopsies. Most data were obtained after exposure to cold and dry air at rest or during exercise. Whether training affects epithelial and inflammatory cells in small airways is unknown. OBJECTIVES: To test whether endurance training under standard environmental conditions causes epithelial damage and inflammation in the small airways of mice. METHODS AND MEASUREMENTS: Formalin-fixed, paraffin-embedded lung sections were obtained in sedentary (n = 14) and endurance-trained (n = 16) Swiss mice at baseline and after 15, 30, and 45 days of training. The following variables were assessed (m…

Endurance raining damages small airway epithelium in mice

Endurance training increases inflammatory cells in small airways of mice

Beneficial effects of aerobic training+montelukast in children with mild intermittent asthma

Endurance training damages small airway epithelium in mice.

Bronchial hyperresponsiveness (BHR) or exhaled nitric oxide concentration (eNO) do not predict exercise-induced bronchoconstriction (EIB) in atopic children with intermittent asthma

Effects of aerobic training in children with mild intermittent asthma.

Endurance training increases infiammatori cells in small airways of mice.