Foundations of offshore wind turbines: A review
Abstract Offshore wind is a source of clean, renewable energy of great potential value to the power industry in the context of a low carbon society. Rapid development of offshore wind energy depends on a good understanding of technical issues related to offshore wind turbines, which is spurring ongoing research and development programmes. Foundations of offshore wind turbines present one of the main challenges in offshore wind turbine design. This paper reviews the present state of knowledge concerning geotechnical and structural issues affecting foundation types under consideration for the support structures of offshore wind turbines, and provides recommendations for future research and de…
COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up
Coronavirus disease-2019 (COVID-19), a viral respiratory illness caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), may predispose patients to thrombotic disease, both in the venous and arterial circulations, because of excessive inflammation, platelet activation, endothelial dysfunction, and stasis. In addition, many patients receiving antithrombotic therapy for thrombotic disease may develop COVID-19, which can have implications for choice, dosing, and laboratory monitoring of antithrombotic therapy. Moreover, during a time with much focus on COVID-19, it is critical to consider how to optimize the available technology to care for patients without COVID-19 who hav…
Pharmacological Agents Targeting Thromboinflammation in COVID-19: Review and Implications for Future Research.
AbstractCoronavirus disease 2019 (COVID-19), currently a worldwide pandemic, is a viral illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The suspected contribution of thrombotic events to morbidity and mortality in COVID-19 patients has prompted a search for novel potential options for preventing COVID-19-associated thrombotic disease. In this article by the Global COVID-19 Thrombosis Collaborative Group, we describe novel dosing approaches for commonly used antithrombotic agents (especially heparin-based regimens) and the potential use of less widely used antithrombotic drugs in the absence of confirmed thrombosis. Although these therapies may have direct…