MAINZ CONGENITAL BIRTH DEFECT MONITORING SYSTEM

The two most important aims of tho Mainz Congenital Birth Defect Monitoring Syitem wore to find “incidence” rates and to took for etiological causes of congenital malformations. All babies born in Mainz underwent a standardized physical and sonographic examination. Anamnestic data of family history, enviromental factors, drug exposure etc. were collected. Using case controll studies we looked for special correlations between morphologic defects and anamnestic data as factors of risk. The relative risk was calculated as odds ratio. Results: In 1990 and 1991 we examinated 8430 newborns. 656 (7,8%) children had major and 2609 (31,1%) minor malformations. Systemic localisation of major defects:…