0000000000309927

AUTHOR

Matteo Gelati

showing 3 related works from this author

Effects of endurance exercise on serum concentration of calcitonin gene-related peptide (CGRP): A potential link between exercise intensity and heada…

2020

Abstract Background Calcitonin gene-related peptide (CGRP) is a powerful neuropeptide that is strongly involved in headache pain pathogenesis by triggering vasodilation, mast cell degranulation and neurogenic inflammation. This evidence has prompted us to investigate the acute influence of endurance exercise on CGRP concentration in blood. Methods The study population consisted of 48 male amateur runners, who ran a half-marathon distance at 75%–85% of maximal oxygen uptake. Blood was drawn before the run (pre-run) and immediately after each runner ended his trial (post-run). The serum concentration of CGRP was measured with a commercial enzyme-linked immunosorbent assay (ELISA) technique. R…

AdultMalemedicine.medical_specialtyAnti-calcitonin gene-related peptide agentsCalcitonin Gene-Related PeptideClinical BiochemistryVasodilationCalcitonin gene-related peptideRunning03 medical and health sciences0302 clinical medicineEndurance trainingInternal medicinemedicineHumansExerciseMigraineanti-calcitonin gene-related peptide agents ; headache ; migraine ; neuropeptide ; physical activity ; runningNeurogenic inflammationbusiness.industryPhysical activityBiochemistry (medical)HeadacheVO2 max030229 sport sciencesGeneral MedicineMiddle Agedmedicine.diseaseNeuropeptideEndocrinologyMigraineCalcitoninPhysical EnduranceExercise intensityAnti-calcitonin gene-related peptide agents; Headache; Migraine; Neuropeptide; Physical activity; Runningbusiness030217 neurology & neurosurgery
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Prothrombotic State Induced by Middle-Distance Endurance Exercise in Middle-Aged Athletes

2018

AbstractSince the impact of possible prothrombotic factors on blood coagulation resulting from exercise remains elusive, this study investigated the acute effects of middle-distance endurance running on blood coagulation parameters in middle-aged athletes. The study population consisted of 33 male endurance runners who were engaged in a 21.1 km run under competitive conditions. Blood samples were collected before the run, immediately after the run, and 3 hours after run completion. Samples were assessed for activated partial thromboplastin time (APTT), prothrombin time (PT), fibrinogen, D-dimer, factor VIII (FVIII), von Willebrand factor antigen (VWF:Ag), endogenous thrombin potential (area…

AdultMalecongenital hereditary and neonatal diseases and abnormalitiesmedicine.medical_specialtyphysical activity030204 cardiovascular system & hematologyFibrinogenRunningblood coagulation03 medical and health sciences0302 clinical medicineVon Willebrand factorEndurance traininghemic and lymphatic diseasesInternal medicineABO blood group systemvon Willebrand FactormedicineHumansExerciseblood coagulation; hemostasis; physical activity; thrombin generation; Adult; Blood Coagulation; Exercise; Factor VIII; Fibrinogen; Humans; Male; Middle Aged; Partial Thromboplastin Time; Physical Endurance; Running; Thrombin; Thrombosis; von Willebrand Factor; AthletesProthrombin timeFactor VIIImedicine.diagnostic_testbiologyChemistryThrombinFibrinogenThrombosisHematologyMiddle Agedprothrombotic factors blood coagulation sportprothrombotic factorsEndocrinologyCoagulationAthletesthrombin generationHemostasishemostasisPhysical Endurancebiology.proteinPartial Thromboplastin TimeCardiology and Cardiovascular Medicinesportcirculatory and respiratory physiology030215 immunologyPartial thromboplastin timemedicine.drug
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Serum Concentration of Growth Differentiation Factor-15 Is Independently Associated with Global Platelet Function and Higher Fibrinogen Values in Adu…

2017

AbstractGrowth differentiation factor-15 (GDF-15) has recently emerged as a strong and independent predictor of cardiovascular events and mortality. However, the pathophysiological mechanisms underlying this important association remain speculative. This study was aimed to investigate the potential associations between the serum concentration of GDF-15 and clinical or laboratory parameters in a population of ostensibly healthy subjects. The study population consisted of 44 healthy volunteers enrolled from the laboratory staff (14 males and 30 females; mean age, 47 ± 11 years), who had their blood collected for assessing complete blood cell count, GDF-15, serum creatinine, albumin, cardiac t…

AdultBlood PlateletsMalemedicine.medical_specialtyGrowth Differentiation Factor 15Platelet Function TestsPopulationRenal function030204 cardiovascular system & hematologyFibrinogenGrowth Differentiation Factor-15 Platelet Function Fibrinogen03 medical and health scienceschemistry.chemical_compound0302 clinical medicineVon Willebrand factorInternal medicinemedicineHumansPlatelet030212 general & internal medicineeducationGrowth Differentiation Factor-15Analysis of VarianceCreatinineeducation.field_of_studybiologybusiness.industryPlatelet FunctionFibrinogenHematologyMiddle AgedHealthy VolunteersEndocrinologychemistryembryonic structuresLinear Modelsbiology.proteinPopulation studyFemaleGDF15Cardiology and Cardiovascular Medicinebusinessmedicine.drugSeminars in Thrombosis and Hemostasis
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