0000000000311555

AUTHOR

Antoni Pastor

0000-0003-3692-0696

showing 4 related works from this author

Modulation of the Endocannabinoids N-Arachidonoylethanolamine (AEA) and 2-Arachidonoylglycerol (2-AG) on Executive Functions in Human.

2013

Animal studies point to an implication of the endocannabinoid system on executive functions. In humans, several studies have suggested an association between acute or chronic use of exogenous cannabinoids (Δ9-tetrahydrocannabinol) and executive impairments. However, to date, no published reports establish the relationship between endocannabinoids, as biomarkers of the cannabinoid neurotransmission system, and executive functioning in humans. The aim of the present study was to explore the association between circulating levels of plasma endocannabinoids N-arachidonoylethanolamine (AEA) and 2-Arachidonoylglycerol (2-AG) and executive functions (decision making, response inhibition and cognit…

lcsh:MedicineNeuropsychological TestsSocial and Behavioral SciencesPrefrontal cortexReceptores de cannabinoides:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Executive FunctionEndocrinologyCognitionWisconsin Card Sorting TestEndocrinologiaHuman PerformanceMedicinePsychologyendocannabinoid systemPrefrontal cortexlcsh:ScienceProblem SolvingPsychiatryMultidisciplinaryCognitive NeurologyCognitive flexibilityPresa de decisionsCognitionMiddle AgedExecutive functionsexecutive functionsHumanos2-arachidonoylglycerolSubstance abuseEndocannabinoidesMental HealthNeurologyCognicióMedicineFemalelipids (amino acids peptides and proteins):Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Membrane Proteins::Receptors Cell Surface::Receptors G-Protein-Coupled::Receptors Cannabinoid [Medical Subject Headings]Animal behaviorClinical psychology:Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids Unsaturated::Arachidonic Acids [Medical Subject Headings]HumanResearch ArticleAdultN-arachidonoylethanolamine:Psychiatry and Psychology::Mental Disorders::Substance-Related Disorders::Marijuana Abuse [Medical Subject Headings]Polyunsaturated AlkamidesCognitive NeuroscienceDecision MakingArachidonic AcidsGlyceridesYoung AdultCannabinoides -- ReceptorsNeuropsychologyCànnabis:Diseases::Nervous System Diseases::Neurodegenerative Diseases [Medical Subject Headings]Pruebas neuropsicológicasÁcidos araquidónicosHumansFunción ejecutivaBiologyCannabisCannabinoides -- Efectes fisiològics:Anatomy::Nervous System::Central Nervous System [Medical Subject Headings]Behavior:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Endocannabinoids [Medical Subject Headings]business.industrylcsh:RCognitive Psychologymedicine.diseaseIowa gambling taskEnfermedades neurodegenerativasAbuso de marihuanaSistema nervioso central:Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychological Tests::Neuropsychological Tests [Medical Subject Headings]:Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Executive Function [Medical Subject Headings]lcsh:QbusinessDecision makingStroop effectNeuroscienceEndocannabinoids
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Modulation of higher-order olfaction components on executive functions in humans

2015

The prefrontal (PFC) and orbitofrontal cortex (OFC) appear to be associated with both executive functions and olfaction. However, there is little data relating olfactory processing and executive functions in humans. The present study aimed at exploring the role of olfaction on executive functioning, making a distinction between primary and more cognitive aspects of olfaction. Three executive tasks of similar difficulty were used. One was used to assess hot executive functions (Iowa Gambling Task-IGT), and two as a measure of cold executive functioning (Stroop Colour and Word Test-SCWT and Wisconsin Card Sorting Test-WCST). Sixty two healthy participants were included: 31 with normosmia and …

Test de StroopOlfactelcsh:Medicine:Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Thinking::Decision Making [Medical Subject Headings]:Psychiatry and Psychology::Psychological Phenomena and Processes::Psychophysiology::Sensation::Smell [Medical Subject Headings]AudiologyPrefrontal cortex:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Executive FunctionOlfaction Disorderspiriform cortexHyposmiaOlfactory threshold:Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychological Tests::Neuropsychological Tests::Stroop Test [Medical Subject Headings]older-adultsalzheimers-diseaselcsh:SciencePsychiatryMultidisciplinaryCognitive flexibilityCognitionMiddle AgedExecutive functionsSmellCognitive inhibitionNeurology:Diseases::Nervous System Diseases::Neurologic Manifestations::Sensation Disorders::Olfaction Disorders [Medical Subject Headings]FemaleFrontal lobemedicine.symptomPsychologyperformanceResearch ArticleAdultmedicine.medical_specialtyAdolescentOlfactionventromedial prefrontal cortexYoung AdultNeurologiamild cognitive impairmentLòbul frontalPruebas neuropsicológicasmedicineHumansTrastornos del olfatoPsiquiatriaToma de decisionesCognición:Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Cognition [Medical Subject Headings]lcsh:Rdecision-makingOlfactory Perceptionodor identificationdeficits:Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychological Tests::Neuropsychological Tests [Medical Subject Headings]:Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Executive Function [Medical Subject Headings]lcsh:QOlfatoStroop effectdiscrimination
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Moderate-Vigorous Physical Activity across Body Mass Index in Females : Moderating Effect of Endocannabinoids and Temperament

2014

Altres ajuts: This manuscript was supported by grants from Instituto Salud Carlos III (FIS PI11/210 and CIBERobn). Sarah Sauchelli is recipient of a pre-doctoral Grant (2013-17) by IDIBELL. Jose C. Fernández-García is recipient of a 'Rio Hortega' contract from 'Instituto de Salud Carlos III', Madrid, Spain (CM12/00059). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. Endocannabinoids and temperament traits have been linked to both physical activity and body mass index (BMI) however no study has explored how these factors interact in females. The aims of this cross-sectional study were to 1) examine differences…

PhysiologyObesidad:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Index [Medical Subject Headings]Social SciencesDonesÍndice de masa corporalBlood plasmaBiochemistry:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight::Obesity [Medical Subject Headings]Body Mass IndexMorbid obesityEndocrinologyFemalesMedicine and Health SciencesHomeostasisPsychologyPublic and Occupational HealthBody mass index (BMI)Big Five personality traitsmedia_commonMultidisciplinaryQRNeurochemistryMiddle AgedLipidsEating disordersEndocannabinoidesPhysiological ParametersHomeostatic MechanismsEating disordersMedicineHarm avoidanceObesitatFemaleBehavioral and Social Aspects of HealthBioelectrical impedance analysisResearch ArticlePersonality:Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids Unsaturated::Arachidonic Acids [Medical Subject Headings]Adultmedicine.medical_specialtyEsfuerzo físicoMujerSciencemedia_common.quotation_subjectObesitat mòrbidaExerciciMotor ActivityBiology:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Personality::Temperament [Medical Subject Headings]Internal medicinemedicine:Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Physical Exertion [Medical Subject Headings]HumansÁcidos araquidónicosWomenObesitySports and Exercise MedicineTemperamentTrastorns de la conducta alimentàriaExerciseMotivationBehavior:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Endocannabinoids [Medical Subject Headings]Human MovementPhysical activityTemperamentoBody WeightCognitive PsychologyNovelty seekingBiology and Life SciencesModerate-vigorous physical activity (MVPA)NeuroendocrinologyPlasma sanguinimedicine.diseaseObesityMorbid ObesityMetabolismEndocrinology:Check Tags::Female [Medical Subject Headings]Cognitive ScienceTemperamentEnergy MetabolismPhysiological ProcessesBody mass indexNeuroscienceEndocannabinoids
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Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothal…

2015

Endocannabinoids participate in the control of neurogenesis, neural cell death and gliosis. The pharmacological effect of the fatty acid amide hydrolase (FAAH) inhibitor URB597, which limits the endocannabinoid degradation, was investigated in the present study. Cell proliferation (phospho-H3(+) or BrdU(+) cells) of the main adult neurogenic zones as well as apoptosis (cleaved caspase-3(+)), astroglia (GFAP(+)), and microglia (Iba1(+) cells) were analyzed in the hippocampus, hypothalamus and striatum of rats intraperitoneally treated with URB597 (0.3 mg/kg/day) at one dose/4-days resting or 5 doses (1 dose/day). Repeated URB597 treatment increased the plasma levels of the N-acylethanolamine…

AstrocitosNeurobiologia del desenvolupamentAmidohidrolasasCannabinoid receptorCarbamatos:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Intracellular Signaling Peptides and Proteins::Apoptosis Regulatory Proteins::Caspases [Medical Subject Headings]:Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation::Neurogenesis [Medical Subject Headings]medicine.medical_treatment:Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose [Medical Subject Headings]Apoptosis:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight [Medical Subject Headings]chemistry.chemical_compound:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Membrane Proteins::Receptors Cell Surface::Receptors G-Protein-Coupled::Receptors Cannabinoid::Receptor Cannabinoid CB1 [Medical Subject Headings]0302 clinical medicine:Chemicals and Drugs::Organic Chemicals::Carboxylic Acids::Acids Acyclic::Carbamates [Medical Subject Headings]Fatty acid amide hydrolaseReceptor cannabinoide CB1:Organisms::Eukaryota::Animals [Medical Subject Headings]FAAHGliosishealth care economics and organizations:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleosides::Deoxyribonucleosides::Deoxyuridine::Bromodeoxyuridine [Medical Subject Headings]:Chemicals and Drugs::Lipids::Glycerides::Triglycerides [Medical Subject Headings]Original Research0303 health sciencesNeurogenesisBenzamidas:Chemicals and Drugs::Polycyclic Compounds::Steroids::Cholestanes::Cholestenes::Cholesterol [Medical Subject Headings]Endocannabinoid systemEtanolaminas3. Good healthEndocannabinoides:Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids Unsaturated::Fatty Acids Monounsaturated::Oleic Acids [Medical Subject Headings]CannabinoidesMicroglíalipids (amino acids peptides and proteins)medicine.symptomColesterol:Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Terpenes::Cannabinoids [Medical Subject Headings]:Chemicals and Drugs::Lipids::Fatty Acids::Palmitic Acids [Medical Subject Headings]psychological phenomena and processesProliferación celularmedicine.medical_specialtyCerebroNeurogenesiseducationBiologyBromodesoxiuridina:Anatomy::Nervous System::Neuroglia::Microglia [Medical Subject Headings]Triglicéridoslcsh:RC321-571Ácidos oléicosRatas03 medical and health sciencesCellular and Molecular NeuroscienceInternal medicineHipocampomedicineCaspasa 3:Anatomy::Nervous System::Central Nervous System::Brain::Limbic System::Hippocampus [Medical Subject Headings]:Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation [Medical Subject Headings]lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry030304 developmental biologyPalmitoylethanolamide:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Endocannabinoids [Medical Subject Headings]:Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Amidohydrolases [Medical Subject Headings]Cannabinoids:Anatomy::Cells::Neuroglia::Astrocytes [Medical Subject Headings]Peso corporalEnergy metabolism:Anatomy::Nervous System::Central Nervous System::Brain [Medical Subject Headings]:Anatomy::Nervous System::Central Nervous System::Brain::Limbic System::Hypothalamus [Medical Subject Headings]URB597:Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death [Medical Subject Headings]:Diseases::Pathological Conditions Signs and Symptoms::Pathologic Processes::Gliosis [Medical Subject Headings]:Chemicals and Drugs::Organic Chemicals::Amines::Amino Alcohols::Ethanolamines [Medical Subject Headings]Muerte celular:Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats [Medical Subject Headings]EndocrinologyURB597chemistryGliosisnervous systemGlucosaCannabinoidEnergy Metabolism:Chemicals and Drugs::Organic Chemicals::Amides::Benzamides [Medical Subject Headings]HipotálamoÁcidos palmíticos030217 neurology & neurosurgeryNeuroscienceFrontiers in Cellular Neuroscience
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