0000000000312482

AUTHOR

Leonardo Zoccante

showing 3 related works from this author

The collaborative outcomes study on health and functioning during infection times in adults (COH-FIT-Adults): Design and methods of an international …

2022

BACKGROUND: . High-quality comprehensive data on short-/long-term physical/mental health effects of the COVID-19 pandemic are needed. METHODS: . The Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) is an international, multi-language (n=30) project involving >230 investigators from 49 countries/territories/regions, endorsed by national/international professional associations. COH-FIT is a multi-wave, on-line anonymous, cross-sectional survey [wave 1: 04/2020 until the end of the pandemic, 12 months waves 2/3 starting 6/24 months threreafter] for adults, adolescents (14-17), and children (6-13), utilizing non-probability/snowball and representative samp…

GerontologyDISORDERSTRESSOutcome AssessmentIMPACT[SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental healthRA0421well-beingPandemicHealth careOutcome Assessment Health CareadultsMedicineANXIETYCOVID-19; mental health; functioning; physical health; representative; well-being; resilience; survey; international; psychiatry; depression; anxiety; post-traumatic; COH-FIT; children; adolescents; adultsmental health functioning physical health representative well-being resilience survey international psychiatry depression anxiety post-traumatic COH-FIT children adolescents adultadolescentsChildSCALEPsychiatryeducation.field_of_study[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyPublic Health Global Health Social Medicine and Epidemiologyadolescents; adults; anxiety; children; COH-FIT; COVID-19; depression; functioning; international; mental health; physical health; post-traumatic; psychiatry; representative; resilience; survey; well-being;psychiatryPsychiatry and Mental healthClinical PsychologyrepresentativeinternationaldepressionProfessional associationLife Sciences & Biomedicinemental healthpost-traumaticPsychopathologyResearch PaperAdultCoronavirus disease 2019 (COVID-19)AdolescentPopulationClinical NeurologyBFfunctioningCOH-FIT; COVID-19; adolescents; adults; anxiety; children; depression; functioning; international; mental health; physical health; post-traumatic; psychiatry; representative; resilience; survey; well-being; Adolescent; Adult; Anxiety; Child; Cross-Sectional Studies; Depression; Humans; Mental Health; Outcome Assessment Health Care; SARS-CoV-2; COVID-19; PandemicschildrenIntervention (counseling)MANAGEMENTHumanssurveyVALIDITYeducationPandemicsresilienceScience & Technologybusiness.industrySARS-CoV-2MORTALITYCOVID-19CAREMental healthHealth CareFolkhälsovetenskap global hälsa socialmedicin och epidemiologiCross-Sectional Studies[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental healthadolescents; adults; anxiety; children; COH-FIT; COVID-19; depression; functioning; international; mental health; physical health; post-traumatic; psychiatry; representative; resilience; survey; well-being; Adolescent; Adult; Anxiety; Child; Cross-Sectional Studies; Depression; Humans; Mental Health; Outcome Assessment Health Care; SARS-CoV-2; COVID-19; PandemicsCOH-FITNeurosciences & Neurologybusinessphysical health[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Disruption of the ASTN2 / TRIM32 locus at 9q33.1 is a risk factor in males for Autism Spectrum Disorders, ADHD and other neurodevelopmental phenotypes

2014

Rare copy number variants (CNVs) disrupting ASTN2 or both ASTN2 and TRIM32 have been reported at 9q33.1 by genome-wide studies in a few individuals with neurodevelopmental disorders (NDDs). The vertebrate-specific astrotactins, ASTN2 and its paralog ASTN1, have key roles in glial-guided neuronal migration during brain development. To determine the prevalence of astrotactin mutations and delineate their associated phenotypic spectrum, we screened ASTN2/TRIM32 and ASTN1 (1q25.2) for exonic CNVs in clinical microarray data from 89 985 individuals across 10 sites, including 64 114 NDD subjects. In this clinical dataset, we identified 46 deletions and 12 duplications affecting ASTN2. Deletions o…

MaleReceptors Cell Surface/geneticsAutismChild Development Disorders Pervasive/geneticsGene ExpressionGenome-wide association studyMedical and Health SciencesTripartite Motif ProteinsRisk FactorsReceptors2.1 Biological and endogenous factorsProtein IsoformsNerve Tissue Proteins/geneticsCopy-number variationAetiologyChildGenetics (clinical)Sequence DeletionPediatricGenetics & HeredityGeneticseducation.field_of_studySingle NucleotideArticlesGeneral MedicineExonsBiological SciencesMental HealthPhenotypeAutism spectrum disorderOrgan SpecificityCerebellar cortexChild PreschoolCell SurfaceSpeech delayFemalemedicine.symptomTranscription Initiation SiteAttention Deficit Disorder with Hyperactivity/geneticsChromosomes Human Pair 9HumanPair 9AdultPediatric Research InitiativeChild Development DisordersAdolescentDNA Copy Number VariationsIntellectual and Developmental Disabilities (IDD)Ubiquitin-Protein LigasesPopulationTranscription Factors/geneticsNerve Tissue ProteinsReceptors Cell SurfaceBiologyPolymorphism Single NucleotideChromosomesYoung AdultClinical ResearchProtein Isoforms/geneticsBehavioral and Social ScienceGeneticsmedicineAttention deficit hyperactivity disorderHumansGenetic Predisposition to DiseasePolymorphismPreschooleducationMolecular BiologyGenetic Association StudiesPervasiveGlycoproteinsHuman GenomeNeurosciencesInfant NewbornGlycoproteins/geneticsInfantNewbornmedicine.diseaseBrain DisordersAttention Deficit Disorder with HyperactivityChild Development Disorders PervasiveCase-Control StudiesAutismTranscription Factors
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Physical and mental health impact of COVID-19 on children, adolescents, and their families: The Collaborative Outcomes study on Health and Functionin…

2022

BACKGROUND: The COVID-19 pandemic has altered daily routines and family functioning, led to closing schools, and dramatically limited social interactions worldwide. Measuring its impact on mental health of vulnerable children and adolescents is crucial. METHODS: The Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT - www.coh-fit.com) is an on-line anonymous survey, available in 30 languages, involving >230 investigators from 49 countries supported by national/international professional associations. COH-FIT has thee waves (until the pandemic is declared over by the WHO, and 6-18 months plus 24-36 months after its end). In addition to adults, COH-FIT also…

GerontologyDISORDER[SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental healthPsychological intervention*Physical healthAdolescentsHVAdolescents; Children; Covid-19; Mental health; Pandemic; Physical health; ResilienceRA0421PandemicCovid-19; Pandemic; Mental health; Physical health; Resilience; Children; AdolescentsMedicineAdolescents; Children; Covid-19; Mental health; Pandemic; Physical health; Resilience; Adolescent; Adult; Child; Cross-Sectional Studies; Health Promotion; Humans; Mental Health; Pandemics; Quality of Life; SARS-CoV-2; COVID-19ChildChildrenSCALEmedia_commonPsychiatry[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology*PandemicPublic Health Global Health Social Medicine and Epidemiology*ResiliencePsychiatry and Mental healthClinical PsychologyProfessional associationMental healthPsychological resilience*Mental healthCovid-19Life Sciences & BiomedicinePsychopathologyCovid-19 Pandemic Mental health Physical health Resilience Children AdolescentsAdultAdolescent*Adolescentsmedia_common.quotation_subjectClinical NeurologyBFPhysical healthHealth PromotionArticle*ChildrenQuality of life (healthcare)Intervention (counseling)HumansVALIDITYPandemicsScience & TechnologyPandemicResiliencebusiness.industrySARS-CoV-2Mental health*Covid-19Folkhälsovetenskap global hälsa socialmedicin och epidemiologiCross-Sectional Studies[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental healthQuality of LifeNeurosciences & Neurologybusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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