0000000000313946

AUTHOR

Andreas Neff

showing 2 related works from this author

Factors associated with epiphora following orbital‐sparing maxillectomy via modified Weber–Ferguson incision with lower blepharoplasty

2021

Purpose The aims of the study were to estimate the frequency of epiphora and to identify factors associated with epiphora after orbital-sparing maxillectomy via modified Weber-Ferguson incision with lower blepharoplasty (OSOSM-MWFILB). Methods We performed a retrospective cohort study enrolling a sample derived from the patient population undergoing OSM-MWFILB over a 7-year period. The predictor variables were grouped into demographic, related health status, anatomic, tumor-specific, and therapeutic categories. The primary outcome variable was the presence of postmaxillectomy epiphora (PME). Descriptive, univariate, and multivariate regression mixed-effect models were computed. Results The …

AdultBlepharoplastyMaleBlepharoplastymedicine.medical_specialtyMultivariate statisticsmedicine.medical_treatment03 medical and health sciences0302 clinical medicineNeoplasmsMaxillamedicineOperating timeHumansIn patientAgedRetrospective StudiesAged 80 and overLacrimal Apparatus DiseasesTumor sizebusiness.industryUnivariateRetrospective cohort studyGeneral MedicineMiddle AgedPrognosisSurgeryOncology030220 oncology & carcinogenesisCarcinoma Squamous CellFemale030211 gastroenterology & hepatologySurgerybusinessComplicationOrbitOrgan Sparing TreatmentsFollow-Up StudiesJournal of Surgical Oncology
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Osteoporosis and bisphosphonates-related osteonecrosis of the jaw: Not just a sporadic coincidence-a multi-centre study

2011

Abstract Introduction Bisphosphonates (BPs) are powerful drugs that inhibit bone metabolism. Adverse side effects are rare but potentially severe such as bisphosphonate-related osteonecrosis of the jaw (BRONJ). To date, research has primarily focused on the development and progression of BRONJ in cancer patients with bone metastasis, who have received high dosages of BPs intravenously. However, a potential dilemma may arise from a far larger cohort, namely the millions of osteoporosis patients on long-term oral BP therapy. Patients and methods This current study assessed 470 cases of BRONJ diagnosed between 2004 and 2008 at eleven different European clinical centres and has resulted in the …

medicine.medical_specialtyTime FactorsSettore MED/09 - Medicina Internamedicine.medical_treatmentOral Surgical ProceduresOsteoporosisAdministration OralSettore MED/28 - Malattie OdontostomatologicheInternal medicinemedicineHumansMedical historyAdverse effectBone Density Conservation AgentsDiphosphonatesDose-Response Relationship Drugbusiness.industryContraindicationsOsteonecrosisBisphosphonatemedicine.diseaseSurgeryZoledronic acidOtorhinolaryngologyCohortOral and maxillofacial surgeryOsteoporosisSurgeryOral Surgeryosteoporosis bisphosphonates ostenecrosis jawsOsteonecrosis of the jawbusinessJaw Diseasesmedicine.drug
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