0000000000314533
AUTHOR
Patrick Willems
Greenhouse gas emissions from integrated urban drainage systems: where do we stand?
Integrated urban drainage systems (IUDS) (i.e., sewer systems, wastewater treatment plants and receiving water bodies) contribute to climate change being sources of greenhouse gas emissions (GHG). This paper, produced by the International Working Group on Data and Models, which works under the IWA/IAHR Joint Committee on Urban Drainage, reviews the state-of-the-art and the recently developed modelling tools used to understand and manage GHG emissions from IUDS. Further, open problems and research gaps are discussed, while proposing a framework for handling GHG from IUDS. The literature review reveals that there is a need to strengthen and partially adequate already available mathematical mo…
Novel mutations including deletions of the entire OFD1 gene in 30 families with type 1 orofaciodigital syndrome : a study of the extensive clinical variability
OFD1, now recognized as a ciliopathy, is characterized by malformations of the face, oral cavity and digits, and is transmitted as an X-linked condition with lethality in males. Mutations in OFD1 also cause X-linked Joubert syndrome (JBTS10) and Simpson-Golabi-Behmel syndrome type 2 (SGBS2). We have studied 55 sporadic and six familial cases of suspected OFD1. Comprehensive mutation analysis in OFD1 revealed mutations in 37 female patients from 30 families; 22 mutations have not been previously described including two heterozygous deletions spanning OFD1 and neighbouring genes. Analysis of clinical findings in patients with mutations revealed that oral features are the most reliable diagnos…
Greenhouse gas emissions from integrated urban drainage systems: where do we stand?
As sources of greenhouse gas (GHG) emissions, integrated urban drainage systems (IUDSs) (i.e., sewer systems, wastewater treatment plants and receiving water bodies) contribute to climate change. This paper, produced by the International Working Group on Data and Models, which works under the IWA/IAHR Joint Committee on Urban Drainage, reviews the state-of-the-art and modelling tools developed recently to understand and manage GHG emissions from IUDS. Further, open problems and research gaps are discussed and a framework for handling GHG emissions from IUDSs is presented. The literature review reveals that there is a need to strengthen already available mathematical models for IUDS to take …
Lessons from the 2018-2019 European droughts : a collective need for unifying drought risk management
Funding Information: This open-access publication was funded by the University of Freiburg. Funding Information: Financial support. The project is supported by the Wassernetzwerk Baden-Württemberg (Water Research Network of the State Baden-Württemberg), which is funded by the Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg (Ministry of Science, Research and the Arts of the State Baden-Württemberg) (grant no. AZ. 7532.21/2.1.6) and Maa-ja vesitekniikan tuki ry foundation. Doris E. Wendt acknowledges her support as part of the NERC-funded Groundwater Drought Initiative (NE/R004994/1). Lucy J. Barker was supported by the Natural Environment Research Council (NE/R016429/1) a…