0000000000315047
AUTHOR
Patricia Parnet
showing 13 related works from this author
Protein expression in submandibular glands of young rats is modified by a high-fat/high-sugar maternal diet
2018
International audience; OBJECTIVE: Maternal diet has consequences on many organs of the offspring, but salivary glands have received little attention despite the importance of the saliva secretory function in oral health and control of food intake. The objective of this work was therefore to document in rats the impact of maternal high-fat/high-sugar diet (Western Diet) on submandibular glands of the progeny. DESIGN: Sprague-Dawley rat dams were fed either a Western diet or control diet during gestation and lactation and their pups were sacrificed 25 days after birth. The pups' submandibular gland protein content was characterized by means of 2D-electrophoresis followed by LC-MS/MS. Data we…
Consequences of a high sugar/high fat maternal diet on protein expression in young rat salivary glands
2015
Introduction: Early nutrition through maternal diet during pregnancy and breastfeeding was shown to have an impact on obesity in childhood. Experiments on animal models have also indicated alterations regarding taste preferences. In addition, salivary physiology has a documented role in taste preferences and food intake in rodents. The objective of this study was therefore to study the impact of maternal diet on salivary glands’ protein profiles of the offspring.Materials and methods: Female rats received during gestation and lactation either a control (C) or a high fat / high sugar diet (WD for “Western Diet”). 18 offspring rats (9C/9WD) were sacrificed at 25 days of age, i.e. shortly afte…
Perinatal Western Diet Consumption Leads to Profound Plasticity and GABAergic Phenotype Changes within Hypothalamus and Reward Pathway from Birth to …
2017
This article is part of the Research Topic Early Life Origins of Obesity and Type 2 Diabetes.; International audience; Perinatal maternal consumption of energy dense food increases the risk of obesity in children. This is associated with an overconsumption of palatable food that is consumed for its hedonic property. The underlying mechanism that links perinatal maternal diet and offspring preference for fat is still poorly understood. In this study, we aim at studying the influence of maternal high-fat/high-sugar diet feeding [western diet (WD)] during gestation and lactation on the reward pathways controlling feeding in the rat offspring from birth to sexual maturity. We performed a longit…
The sensory and nutritional experience of parents guide offsprings' feeding behavior
2016
Le comportement alimentaire est régulé par des facteurs physiologiques intrinsèques et est largement influencé par l’environnement culturel. Une prise alimentaire excessive et un mode de vie trop sédentaire sont les principales raisons de l’épidémie mondiale d’obésité. Si l’influence du contexte familial sur les habitudes alimentaires ne fait aucun doute, le fait que l’état nutritionnel, métabolique et hormonal des parents avant la conception, puis de la mère pendant la gestation et l’allaitement puisse influencer le comportement alimentaire futur de l’enfant est un concept novateur qui ouvre la voie à des mesures de prévention. Au cours des dernières décennies, des travaux sur des cohortes…
L'expression protéique dans les glandes salivaires est impactée par un régime maternel de type Western-Diet chez le rat
2016
Methodologie, recherche et revue; L'expression protéique dans les glandes salivaires est impactée par un régime maternel de type Western-Diet chez le rat. Journées francophones de nutrition (JFN)
Perinatal high-fat diet increases hippocampal vulnerability to the adverse effects of subsequent high-fat feeding
2015
Epidemiological observations report an increase in fat consumption associated with low intake of n-3 relative to n-6 polyunsaturated fatty acids (PUFAs) in women of childbearing age. However, the impact of these maternal feeding habits on cognitive function in the offspring is unknown. This study aims to investigate the impact of early exposure to a high-fat diet (HFD) with an unbalanced n-6/n-3 PUFAs ratio on hippocampal function in adult rats. Furthermore, we explored the effects of perinatal HFD combined with exposure to HFD after weaning. Dams were fed a control diet (C, 12% of energy from lipids, n-6/n-3 PUFAs ratio: 5) or HFD (HF, 39% of energy from lipids, n-6/n-3 PUFAs ratio: 39) th…
Maternal Western Diet” feeding of rat dams leads to profound plasticity and GABAergic phenotype changes within reward pathway from birth to sexual ma…
2017
National audience
Consequences of a high sugar/high fat maternal diet on protein expression in young rat submandibular glands
2015
Consequences of a high sugar/high fat maternal diet on protein expression in young rat submandibular glands. Congrès français de Spectrométrie de Masse et d'Analyse Protéomique (SMAP 2015)
Impact of perinatal high fat diet on metabolic parameters, visual function and behaviour in adulthood
2011
National audience
Impact of perinatal over-nutrition on the developing sweet/fatty taste and the ontogeny of brain reward pathway, from birth to sexual maturity in rat
2015
National audience
Perinatal Western Diet consumption leads to a profound change in plasticity and GABAergic phenotype within hypothalamus and reward pathway from birth…
2016
National audience
Impact of an unbalanced diet on the acquisition of food preferences and the development of reward circuits in rat
2018
International audience
Consuming a balanced diet from weaning reverses the programming of food preferences in offspring of Western-Diet-fed rat dams
2017
National audience