0000000000315136
AUTHOR
Laurent Najman
Improved estimation of the left ventricular ejection fraction using a combination of independent automated segmentation results in cardiovascular magnetic resonance imaging
—This work aimed at combining different segmenta-tion approaches to produce a robust and accurate segmentation result. Three to five segmentation results of the left ventricle were combined using the STAPLE algorithm and the reliability of the resulting segmentation was evaluated in comparison with the result of each individual segmentation method. This comparison was performed using a supervised approach based on a reference method. Then, we used an unsupervised statistical evaluation, the extended Regression Without Truth (eRWT) that ranks different methods according to their accuracy in estimating a specific biomarker in a population. The segmentation accuracy was evaluated by focusing o…
Definition of a mutual reference shape based on information theory and active contours
In this paper, we propose to consider the estimation of a reference shape from a set of different segmentation results using both active contours and information theory. The reference shape is then defined as the minimum of a criterion that benefits from both the mutual information and the joint entropy of the input segmentations. This energy criterion is here justified using similarities between information theory quantities and area measures, and presented in a continuous variational framework. This framework brings out some interesting evaluation measures such as the specificity and sensitivity. In order to solve this shape optimization problem, shape derivatives are computed for each te…
Comparison of different segmentation approaches without using gold standard. Application to the estimation of the left ventricle ejection fraction from cardiac cine MRI sequences.
International audience; A statistical method is proposed to compare several estimates of a relevant clinical parameter when no gold standard is available. The method is illustrated by considering the left ventricle ejection fraction derived from cardiac magnetic resonance images and computed using seven approaches with different degrees of automation. The proposed method did not use any a priori regarding with the reliability of each method and its degree of automation. The results showed that the most accurate estimates of the ejection fraction were obtained using manual segmentations, followed by the semiautomatic methods, while the methods with the least user input yielded the least accu…
A reference free approach for the comparative evaluation of eight segmentation methods for the estimation of the left ventricular ejection fraction in cardiac MRI.
International audience; Objective evaluation and comparison of segmentation algorithms for medical imaging is still a challenging issue. The most frequently used evaluation method consists in comparing the segmentation with a manual delineation. Since obtaining such manual segmentation can be tedious, we proposed a method based on the "extended Regression Without Truth" approach (eRWT)(1). This approach is applied to the comparative evaluation of 8 segmentation algorithms with different degrees of automation from the estimated left ventricular ejection fraction (LVEF).