0000000000315714

AUTHOR

Pietro Abate

showing 3 related works from this author

Increased airway inflammatory cells in endurance athletes: what do they mean?

2003

Background Inflammatory cells are increased in the airways of end urance athletes, but their role in causing exercise-induced respiratory symptoms and bronchoconstriction, or their possible long-term consequences, are uncertain. Aim To put the results of athlete studies in perspective, by analysing the pathogenesis of airway cell changes and their impact on respiratory function. Results Athletes of different endurance sports at rest showed increased airway neutrophils. Elite swimmers and skiers also showed large increases in airway eosinophils and lymphocytes, possibly related to chronic, exercise-related exposure to irritants or cold and dry air, respectively. Post-exercise studies reporte…

business.industryImmunologyInflammationrespiratory systemrespiratory tract diseasesEndurance trainingExhaled nitric oxideImmunologymedicineImmunology and AllergyBronchoconstrictionRespiratory functionExpirationmedicine.symptomRespiratory systemAirwaybusinessClinical & Experimental Allergy
researchProduct

Circulating hematopoietic progenitor cells in runners

2002

Because endurance exercise causes release of mediators and growth factors active on the bone marrow, we asked whether it might affect circulating hematopoietic progenitor cells (HPCs) in amateur runners [ n = 16, age: 41.8 ± 13.5 (SD) yr, training: 93.8 ± 31.8 km/wk] compared with sedentary controls ( n = 9, age: 39.4 ± 10.2 yr). HPCs, plasma cortisol, interleukin (IL)-6, granulocyte colony-stimulating factor (G-CSF), and the growth factor fms-like tyrosine kinase-3 (flt3)-ligand were measured at rest and after a marathon (M; n = 8) or half-marathon (HM; n = 8). Circulating HPC counts (i.e., CD34+cells and their subpopulations) were three- to fourfold higher in runners than in controls at b…

AdultMalemedicine.medical_specialtyMarathonTime FactorsHydrocortisonePhysiologymedicine.medical_treatmentPhysical Therapy Sports Therapy and RehabilitationAntigens CD34Settore MED/10 - Malattie Dell'Apparato RespiratorioSettore BIO/09 - FisiologiaRunningEndocrinologyReference ValuesEndurance trainingPhysiology (medical)Internal medicineGranulocyte Colony-Stimulating FactormedicineHumansOrthopedics and Sports MedicineProgenitor cellCytokineBlood CellsPhysical Education and TrainingHematopoietic cellInterleukin-6business.industryGrowth factorMembrane ProteinsGrowth factorMiddle AgedHematopoietic Stem CellsEndurance trainingBlood Cell CountCytokinemedicine.anatomical_structureEndocrinologyembryonic structuresImmunologyPhysical EnduranceHematopoietic progenitor cellsBone marrowCytokines; Endurance training; Growth factors; Marathon; Physiology; Endocrinology; Orthopedics and Sports Medicine; Physical Therapy Sports Therapy and Rehabilitationbusinesshuman activities
researchProduct

Airway cells after swimming outdoors or in the sea in nonasthmatic athletes

2003

BONSIGNORE, M. R., G. MORICI, L. RICCOBONO, M. PROFITA, A. BONANNO, A. PATERNO, R. DI GIORGI, L. CHIMENTI, P. ABATE, F. MIRABELLA, A. M. VIGNOLA, and G. BONSIGNORE. Airway Cells after Swimming Outdoors or in the Sea in Nonasthmatic Athletes. Med. Sci. Sports Exerc., Vol. 35, No. 7, pp. 1146–1152, 2003. Marathon runners and elite swimmers showed increased inflammatory cells in the airways at baseline. Although airway neutrophils increase further after a marathon race, the airway response to swimming is unknown. The aim of this study was to assess the effects of swimming on airway cells. To avoid the concomitant effects of chronic exposure to chlorine, the study was conducted in seven nonasth…

AdultSpirometrymedicine.medical_specialtyAdolescentRespiratory SystemPhysical Therapy Sports Therapy and RehabilitationNitric OxideNeutrophil ActivationRunningEndurance trainingInternal medicinemedicineHumansOrthopedics and Sports MedicineExpirationRespiratory systemSwimmingInflammationEosinophil cationic proteinmedicine.diagnostic_testbusiness.industryrespiratory systemEosinophilRespiratory Function Testsrespiratory tract diseasesSurgerymedicine.anatomical_structureEndocrinologyBreath TestsExhaled nitric oxidePhysical EndurancebusinessAirway
researchProduct