0000000000319281
AUTHOR
Alla Tereshchenko
Novel Immune TiO2 Photoluminescence Biosensors for Leucosis Detection
Abstract Novel immune photoluminescent biosensor, based on TiO2 nanoparticles, for retroviral leucosis detection has been developed. The photoluminescence spectra were excited by solid state laser with wavelength 355 nm and measured in the range of 370-800 nm. Original photoluminescence spectrum of TiO2 nanoparticles showed wide maximum at 515 nm. The biosensitive layer was formed by immobilization of retroviral leucosis antigens on the surface of TiO2 nanoparticles. Immobilization of antigens on TiO2 surface led to UV-shift of photoluminescence spectrum and increase of PL intensity. The response to different concentrations of retroviral leucosis antibodies has been measured. The decrease o…
Optical biosensors based on ZnO nanostructures: advantages and perspectives. A review
This review article highlights the application of beneficial physico-chemical properties of ZnO nanostructures for the detection of wide range of biological compounds. As the medical diagnostics require accurate, fast and inexpensive biosensors, the advantages inherent optical methods of detection are considered. The crucial points of the immobilization process, responsible for biosensor performance (biomolecule adsorption, surface properties, surface defects role, surface functionalization etc.) along with the interaction mechanism between biomolecules and ZnO are disclosed. The latest achievements in surface plasmon resonance (SPR), surface enhanced Raman spectroscopy (SERS) and photolumi…