0000000000319300

AUTHOR

Laura De Campos Hildebrand

showing 2 related works from this author

Evaluation of cell proliferation rate in non-dysplastic leukoplakias

2008

Objective: Analyze whether the most frequent cases of non-dysplastic leukoplakias, hyperkeratosis (H), acanthosis (A), and hyperkeratosis with acanthosis (HA) have similar cell proliferation rates and to compare them with epithelial dysplastic (ED) leukoplakias and normal oral epithelium (NOE).Study design: The sample comprised 10 cases of normal oral epithelium, 10 cases of hyperkeratosis, 10 cases of acanthosis, 10 cases of hyperkeratosis with acanthosis and 10 cases of epithelial dysplasia. The mean number of AgNORs per nucleus (mAgNOR) and the mean percentage of cells with 1, 2, 3 and 4 or more AgNORs per nucleus (pAgNOR) were recorded. Results: The results of mAgNOR showed differences …

MaleEpithelial dysplasiaPathologymedicine.medical_specialtyHyperkeratosisAcanthosisHyperkeratosisEpithelial dysplasiaAcanthosisBasal (phylogenetics)Biological profileProliferation rateOral and maxillofacial pathologyHumansMedicineLeucoplasia bucalGeneral DentistryCell proliferationCell ProliferationLeukoplakiabusiness.industryAntigens NuclearProliferação celularMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Doencas [Mucosa bucal]AgNORstomatognathic diseasesOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASPatologia bucalFemaleSurgeryLeukoplakia OralbusinessLeukoplakia
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Non-muscle myosin II as a predictive factor in head and neck squamous cell carcinoma

2018

Background The present study attempted to provide information regarding non-muscle myosin II (MII) isoforms immunoreactivity in patients with head and neck squamous cell carcinoma (HNSCC) and analysis of the patients’ clinical status after 5 years of monitoring. Material and Methods A semiquantitative analysis of the immunoreactivity of the MII isoforms was performed in 54 surgical specimens and its correlation with clinical and pathological variables and prognosis was verified. Data were analyzed using chi-square, Mann-Whitney and Kruskal-Wallis tests. To evaluate the survival over the total monitoring time and any connection with the proteins studied, the Kaplan-Meier analysis was used. P…

Gene isoformPathologymedicine.medical_specialtyMetastasis03 medical and health sciences0302 clinical medicineText miningMyosinBiomarkers TumormedicineHumansGeneral DentistryPathologicalMyosin Type IINon muscle myosinOral Medicine and PathologySquamous Cell Carcinoma of Head and Neckbusiness.industryResearch030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Prognosismedicine.diseaseHead and neck squamous-cell carcinomaPredictive factorOtorhinolaryngologyHead and Neck NeoplasmsUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellSurgerybusiness
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