0000000000324522

AUTHOR

Berthold Seitz

showing 4 related works from this author

Hornhaut: endotheliale Dystrophien, endotheliale Degenerationen

2014

Dieser Ubersichtsartikel bietet einen kurzen Uberblick uber die endothelialen Hornhautdystrophien (HD) und Degenerationen, deren primare Storung im Bereich des einschichtigen Endothels bzw. der Descemet-Membran liegt, sowie deren Therapie. Hornhautendotheldegenerationen sind definiert als Veranderungen des Endothels aufgrund von Alterungsprozessen oder durch Trauma (z. B. nach Kataraktchirurgie). Hornhautdystrophien beschreiben eine Vielzahl verschiedener erblicher Krankheitsbilder, bei denen meist ein bilateraler, nahezu ausschlieslicher Befall der Hornhaut vorliegt. Die Vererbung ist meist autosomal-dominant, kann aber auch autosomal-rezessiv und X-chromosomal-dominant sein.

Ophthalmologymedicine.medical_specialtymedicine.anatomical_structurebusiness.industryOphthalmologyCorneamedicineGeneral EngineeringbusinessAugenheilkunde up2date
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Lattice Corneal Dystrophy Type 1

2014

PURPOSE To evaluate the question whether lattice corneal dystrophy type 1 (LCD1) is of epithelial or stromal origin. METHODS The landmark of advanced LCD1 shows central superficial haze and paracentral stromal lattice lines. In 16 eyes of 8 affected individuals of 2 families, a penetrating keratoplasty was performed. The follow-up was 8 to 16 years after penetrating keratoplasty. Slit-lamp documentation of the patients was evaluated in direct and indirect illumination with dilated pupil to assess the horizontal and vertical pattern of new deposits on the corneal graft. Three affected patients of 2 families are demonstrated in detail. A DNA analysis was performed. RESULTS Gene identification…

AdultMalemedicine.medical_specialtyStromal cellCorneal StromaDNA Mutational AnalysisCorneal graftCorneal KeratocytesCorneal erosionDirect illuminationTransforming Growth Factor betaOphthalmologyTGFBI genemedicineHumansCorneal Dystrophies HereditaryExtracellular Matrix Proteinsbusiness.industryEpithelium Cornealmedicine.diseaseeye diseasesOphthalmologyMutationLattice corneal dystrophyFemalebusinessKeratoplasty PenetratingTGFBICornea
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SARS-CoV-2: Impact on, Risk Assessment and Countermeasures in German Eye Banks.

2020

Introduction Since the beginning of the COVID-19 pandemic there has been some debate regarding the risk of transmission through tissue transplantation and tissue banking processes. Aim of the study To analyze the changes that SARS-CoV-2 has caused regarding the harvesting of corneal donor tissue and eye bank activities in Germany. Methods A questionnaire was provided to 26 eye banks in Germany, consisting of questions about adaptations made in the screening of potential donors and the harvesting of corneal tissue following the pandemic spread of SARS-CoV-2. Results Eighteen eye banks actively reduced recruitment of donors and two banks ceased all activity. Additional diagnostic screening wa…

Face shieldmedicine.medical_specialtybusiness.product_categoryTissue and Organ ProcurementSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MedizinEye BanksRisk AssessmentCorneal DiseasesCorneal Transplantation03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineCorneaGermanySurveys and QuestionnairesPandemicmedicineDisease Transmission InfectiousHumansIntensive care medicinebusiness.industrySARS-CoV-2COVID-19Eye bankSensory SystemsTissue DonorsTransplantationOphthalmologymedicine.anatomical_structureMedical CountermeasuresDonationPractice Guidelines as TopicQuarantine030221 ophthalmology & optometryTissue and Organ Harvestingsense organsRisk assessmentbusiness030217 neurology & neurosurgeryCurrent eye research
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IC3D Classification of Corneal Dystrophies—Edition 2

2015

To update the 2008 International Classification of Corneal Dystrophies (IC3D) incorporating new clinical, histopathologic, and genetic information.The IC3D reviewed worldwide peer-reviewed articles for new information on corneal dystrophies published between 2008 and 2014. Using this information, corneal dystrophy templates and anatomic classification were updated. New clinical, histopathologic, and confocal photographs were added.On the basis of revisiting the cellular origin of corneal dystrophy, a modified anatomic classification is proposed consisting of (1) epithelial and subepithelial dystrophies, (2) epithelial-stromal TGFBI dystrophies, (3) stromal dystrophies, and (4) endothelial d…

Macular corneal dystrophygenetic structuresEndothelial dystrophiesGenetic diseaseStromaEpitheliumGelatinousdrop-like corneal dystrophyCorneaLisch Epithelial Corneal DystrophyCornea pathologyPosteror polymorphous corneal dystrophyCorneal Dystrophies HereditaryPosterior amorphous corneal dystrophyEpithelial-stromal TGFBI dystrophiesMacular corneal dystrophyFleck corneal dystrophyLattice corneal dystrophyPre-Descemet corneal dystrophyCongenital stromal corneal dystrophySubepithelialmucinous corneal dystrophySchnyder corneal dystrophyThiel-Behnke corneal dystrophyPosterior polymorphous corneal dystrophyEpithelial and subepithelial dystrophiesFuchsendothelial corneal dystrophyFleck corneal dystrophyReis-Bücklers corneal dystrophyCongenital hereditary endothelial dystrophyCentralcloudy dystrophy of FrançoisCongenital stromal corneal dystrophyPosterior amorphous corneal dystrophymedicine.medical_specialtyHistologyeducationHereditary diseaseHistopathologyBiologyKeratoconusLisch epithelial corneal dystrophyMeesmann dystrophyNOBowman membraneDescemetmembraneInternational Classification of DiseasesTerminology as TopicOphthalmologyGeneticsmedicineHumansBowman membrane; Centralcloudy dystrophy of François; Confocal microscopy; Confocal microscopy; Congenital corneal endothelial dystrophy and X-linked endothelialdystrophy; Congenital stromal corneal dystrophy; Cornea; Cornea; Cornea dystrophy; Cornea pathology; Descemetmembrane; Endothelial dystrophies; Endothelium; Epithelial and subepithelial dystrophies; Epithelial basement membranedystrophy; Epithelial recurrent erosion dystrophies; Epithelial-stromal TGFBI dystrophies; Epithelium; Fleck corneal dystrophy; Fuchsendothelial corneal dystrophy; Gelatinousdrop-like corneal dystrophy; Genetic disease; Genetics; Granular corneal dystrophy type 1; Granular corneal dystrophy type 2; Hereditary disease; Histology; Histopathology; Keratoconus; Lattice corneal dystrophy; Lisch epithelial corneal dystrophy; Macular corneal dystrophy; Meesmann dystrophy; Posterior amorphous corneal dystrophy; Posteror polymorphous corneal dystrophy; Pre-Descemet corneal dystrophy; Reis-Bücklers corneal dystrophy; Schnyder corneal dystrophy; Stroma; Stromal dystrophies; Subepithelialmucinous corneal dystrophy; TGFBI; Thiel-Behnke corneal dystrophy; OphthalmologyEndotheliumEpithelial basement membranedystrophyCornea dystrophyCongenital corneal endothelial dystrophy and X-linked endothelialdystrophymedicine.diseaseeye diseasesConfocal microscopyOphthalmologyGranular corneal dystrophy type 2Granular corneal dystrophy type 1Stromal dystrophiesLattice corneal dystrophysense organsTGFBIEpithelial recurrent erosion dystrophiesCornea
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