0000000000325663

AUTHOR

Silvia Serrano

showing 6 related works from this author

Incidence of severe critical events in paediatric anaesthesia (APRICOT): a prospective multicentre observational study in 261 hospitals in Europe

2017

Background Little is known about the incidence of severe critical events in children undergoing general anaesthesia in Europe. We aimed to identify the incidence, nature, and outcome of severe critical events in children undergoing anaesthesia, and the associated potential risk factors. Methods The APRICOT study was a prospective observational multicentre cohort study of children from birth to 15 years of age undergoing elective or urgent anaesthesia for diagnostic or surgical procedures. Children were eligible for inclusion during a 2-week period determined prospectively by each centre. There were 261 participating centres across 33 European countries. The primary endpoint was the occurenc…

MalePediatricsHealth StatusOPERATING-ROOMRespiratory Tract DiseasesCHILDREN0302 clinical medicineREGIONAL ANESTHESIAPostoperative Complications030202 anesthesiologyCARDIAC-ARRESTMedicineGeneral anaesthesiaProspective StudiesProspective cohort studyChildIntraoperative ComplicationsCOMPLICATIONSddc:617Incidence (epidemiology)Mortality ratemusculoskeletal neural and ocular physiologyIncidenceAge FactorsHospitalsEuropeCardiovascular DiseasesChild PreschoolRESPIRATORY ADVERSE EVENTSFemaleClinical CompetenceCohort studyPulmonary and Respiratory Medicinemedicine.medical_specialtyAdolescentmacromolecular substancesAnesthesia GeneralDrug Hypersensitivity03 medical and health sciencesMORBIDITYJournal ArticleHumansbusiness.industryInfant NewbornInfant030208 emergency & critical care medicinePerioperativenervous systemPROSPECTIVE COHORTRelative riskRISK-FACTORSObservational studyHuman medicineNervous System DiseasesbusinessSYSTEM
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Fracción aminoterminal del propéptido natriurético cerebral y troponina ultrasensible en el dolor torácico agudo de origen incierto. Un subestudio de…

2013

Resumen Introduccion y objetivos La troponina ultrasensible ha mejorado el diagnostico del sindrome coronario agudo en los pacientes que se presentan con dolor toracico y troponina convencional normal. Nuestro objetivo es analizar si la fraccion aminoterminal del propeptido natriuretico cerebral aporta informacion adicional. Metodos Se estudio a 398 pacientes, incluidos en el estudio PITAGORAS, que acudieron a urgencias por dolor toracico con troponina convencional normal en dos muestras seriadas (a la llegada y a las 6-8 h). Se midio de forma centralizada la troponina T ultrasensible en las dos muestras y la fraccion aminoterminal del propeptido natriuretico cerebral en la segunda. Los obj…

business.industryMedicineCardiology and Cardiovascular MedicinebusinessHumanitiesRevista Española de Cardiología
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Peri-operative red blood cell transfusion in neonates and infants: NEonate and Children audiT of Anaesthesia pRactice IN Europe: A prospective Europe…

2022

BACKGROUND Little is known about current clinical practice concerning peri-operative red blood cell transfusion in neonates and small infants. Guidelines suggest transfusions based on haemoglobin thresholds ranging from 8.5 to 12���g���dl-1, distinguishing between children from birth to day 7 (week 1), from day 8 to day 14 (week 2) or from day 15 (���week 3) onwards. OBJECTIVE To observe peri-operative red blood cell transfusion practice according to guidelines in relation to patient outcome. DESIGN A multicentre observational study. SETTING The NEonate-Children sTudy of Anaesthesia pRactice IN Europe (NECTARINE) trial recruited patients up to 60 weeks' postmenstrual age undergoing anaesthe…

Red Blood Cell TransfusionNEONATEHaemoglobin levels610 Medicine & healthPeri-operative ; red blood cell transfusion ; neonates ; infantsHigh morbidityHemoglobinsTRANSFUSIONmedicineClinical endpointHumansAnesthesiaProspective Studiesbusiness.industryPostmenstrual AgeInfant NewbornPerioperativeEuropeRed blood cellAnesthesiology and Pain Medicinemedicine.anatomical_structureAnesthesiaObservational studybusiness610 Medizin und GesundheitErythrocyte TransfusionEuropean journal of anaesthesiology
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Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE)

2021

Background: Neonates and infants are susceptible to hypoxaemia in the perioperative period. The aim of this study was to analyse interventions related to anaesthesia tracheal intubations in this European cohort and identify their clinical consequences. Methods: We performed a secondary analysis of tracheal intubations of the European multicentre observational trial (NEonate and Children audiT of Anaesthesia pRactice IN Europe [NECTARINE]) in neonates and small infants with difficult tracheal intubation. The primary endpoint was the incidence of difficult intubation and the related complications. The secondary endpoints were the risk factors for severe hypoxaemia attributed to difficult airw…

MaleTime Factorspaediatricmedicine.medical_treatmentmorbiditySeverity of Illness Index0302 clinical medicine030202 anesthesiologyRisk FactorsClinical endpointAnesthesiaProspective Studies610 Medicine & healthHypoxiapaediatric.Medical Auditmedicine.diagnostic_testddc:617infantsIncidence (epidemiology)IncidenceAge Factorsanaesthesiarespiratory systemEuropeTreatment OutcomeAnesthesiaCohortFemalemedicine.symptomBradycardiaLaryngoscopy610 Medicine & healthAnesthesia/adverse effects/mortalityRisk AssessmentEurope/epidemiology03 medical and health sciencesLaryngoscopy/adverse effects/mortalityHypoxia/diagnosis/epidemiology/mortalitymedicineIntubation IntratrachealHumansdifficult intubationLaryngoscopybusiness.industryTracheal intubationInfant NewbornInfantPerioperativeNewborn3126 Surgery anesthesiology intensive care radiologymortalityneonatesClinical trialIntratrachealAnesthesiology and Pain MedicineairwayIntubation Intratracheal/adverse effects/mortalityneonateIntubationbusinessairwaysBritish Journal of Anaesthesia
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Corrigendum to ‘Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE):a pro…

2021

The authors regret that errors were present in the above article. On page 1174, in the second paragraph of the Statistical methods section, the second sentence should read as follows: The incidence of difficult intubation was determined including those whose tracheas were already intubated and is reported as a percentage with a 95% exact binomial CI. On page 1175, in the third paragraph of the Statistical methods section ‘mean standardised difference (MSD)’ should read ‘standardised mean difference (SMD)’ The authors would like to apologise for any inconvenience caused.

Anesthesiology and Pain Medicinebusiness.industrymedicine.medical_treatmentAnesthesiaTracheal intubationNeonates anaesthesiamedicineMEDLINEObservational studyAuditbusiness
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N-terminal Pro-brain Natriuretic Peptide and High-sensitivity Troponin in the Evaluation of Acute Chest Pain of Uncertain Etiology. A PITAGORAS Subst…

2013

Abstract Introduction and objectives High-sensitivity troponin assays have improved the diagnosis of acute coronary syndrome in patients presenting with chest pain and normal troponin levels as measured by conventional assays. Our aim was to investigate whether N-terminal pro-brain natriuretic peptide provides additional information to troponin determination in these patients. Methods A total of 398 patients, included in the PITAGORAS study, presenting to the emergency department with chest pain and normal troponin levels as measured by conventional assay in 2 serial samples (on arrival and 6 h to 8 h later) were studied. The samples were also analyzed in a central laboratory for high-sensi…

MaleChest Painmedicine.medical_specialtyAcute coronary syndromeEndpoint Determinationmedicine.drug_classmedicine.medical_treatmentRevascularizationChest painInternal medicineNatriuretic Peptide BrainmedicineNatriuretic peptideHumansProspective StudiesAcute Coronary SyndromeAgedbiologyTroponin Tbusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseTroponinTroponinConfidence intervalRelative riskbiology.proteinCardiologyFemalemedicine.symptombusinessBiomarkersRevista Española de Cardiología (English Edition)
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