0000000000326301

AUTHOR

E Cavallo

showing 2 related works from this author

Randomized double-blind placebo-controlled trial of acetyl-L-carnitine for ALS.

2013

Our objective was to assess the effects of acetyl-L-carnitine (ALC) with riluzole on disability and mortality of amyotrophic lateral sclerosis (ALS). Definite/probable ALS patients, 40-70 years of age, duration 6-24 months, self-sufficient (i.e. able to swallow, cut food/handle utensils, and walk), and with forced vital capacity (FVC) > 80% entered a pilot double-blind, placebo-controlled, parallel group trial and were followed for 48 weeks. ALC or placebo 3 g/day was added to riluzole 100 mg/day. Primary endpoint: number of patients no longer self-sufficient. Secondary endpoints: changes in ALSFRS-R, MRC, FVC and McGill Quality of Life (QoL) scores. Analysis was made in the intention-to-tr…

Maleamyotrophic lateral sclerosisVital CapacityPlacebo-controlled studyPilot ProjectsGastroenterologylaw.inventionRandomized controlled triallawAcetyl-L-carnitineamyotrophic lateral sclerosis; motor neuron disease; randomized trial; acetyl-l-carnitinerandomized trialAmyotrophic lateral sclerosisAcetylcarnitineALS acetyl-L-carnitineNootropic AgentsRiluzoleMiddle AgedRiluzoleTreatment OutcomeNeurologyCombinationDisease Progressionmotor neuron diseaseDrug Therapy CombinationSettore MED/26 - NeurologiaFemaleAcetylcarnitinemedicine.drugAdultmedicine.medical_specialtyAcetyl-L-carnitine amyotrophic lateral sclerosis motor neuron disease randomized trialDouble blindDouble-Blind MethodDrug TherapyInternal medicinemedicineHumansAgedMED/26 - NEUROLOGIAbusiness.industryDisease progressionmedicine.diseaseAcetyl-L-carnitineSurgeryQuality of LifeAcetylcarnitine; Adult; Aged; Amyotrophic Lateral Sclerosis; Disease Progression; Double-Blind Method; Drug Therapy Combination; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Nootropic Agents; Pilot Projects; Quality of Life; Riluzole; Treatment Outcome; Vital CapacityNeurology (clinical)businessExcitatory Amino Acid Antagonists
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Precision electroweak measurements on the Z resonance

2005

We report on the final electroweak measurements performed with data taken at the Z resonance by the experiments operating at the electron-positron colliders SLC and LEP. The data consist of 17 million Z decays accumulated by the ALEPH, DELPHI, L3 and OPAL experiments at LEP, and 600 thousand Z decays by the SLD experiment using a polarised beam at SLC. The measurements include cross-sections, forward-backward asymmetries and polarised asymmetries. The mass and width of the Z boson, $\MZ$ and $\GZ$, and its couplings to fermions, for example the $\rho$ parameter and the effective electroweak mixing angle, are precisely measured. The number of light neutrino species is determined to be 2.9840…

Top quarkFORWARD-BACKWARD ASYMMETRYPARTICLE PHYSICS; LARGE ELECTRON POSITRON COLLIDER; ALEPH; DELPHI; L3; OPALGeneral Physics and Astronomy01 natural sciences7. Clean energyHigh Energy Physics - ExperimentSettore FIS/04 - Fisica Nucleare e SubnucleareHigh Energy Physics - Experiment (hep-ex)High Energy Physics - Phenomenology (hep-ph)electron-positron physics[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Electroweak interactionPhysicsQuantum chromodynamicsOPALElectron–positron physics; Electroweak interactions; Decays of heavy intermediate gauge bosons; Fermion–antifermion production; Precision measurements at the Z resonance; Tests of the Standard Model; Radiative corrections; Effective coupling constants; Neutral weak current; Z boson; W boson; Top quark; Higgs bosonParticle physics - ExperimentPhysicsSettore FIS/01 - Fisica SperimentaleElectroweak interactionFORWARD-BACKWARD ASYMMETRY; FERMION-PAIR PRODUCTION; HADRONIC-Z-DECAYS; TOP-QUARK MASS; ANGLE BHABHA SCATTERING; W-BOSON MASS; CROSS-SECTION ASYMMETRY; Z-LINE-SHAPE; SEMILEPTONIC BRANCHING RATIOS; CARLO EVENT GENERATORdecays of heavy intermediate gauge bosons; effective coupling constants; electron-positron physics; electroweak interactions; fermion-antifermion production; higgs boson; neutral weak current; precision measurements at the z resonance; radiative corrections; tests of the standard model; top quark; w boson; z bosonRadiative correctionsALEPHLARGE ELECTRON POSITRON COLLIDERRadiative correctionHigh Energy Physics - PhenomenologyFIS/01 - FISICA SPERIMENTALEDecays of heavy intermediate gauge bosonsL3Z-LINE-SHAPEHiggs bosonFERMION-PAIR PRODUCTIONPARTICLE PHYSICSFísica nuclearNeutrinoFermion–antifermion productionPrecision measurements at the Z resonanceTests of the Standard ModelParticle physicsZ bosonfermion-antifermion productionElectroweak interactionsHiggs bosonFOS: Physical sciencesddc:500.2Elementary particle physics ; z boson ; LEP ; electroweakDecays of heavy intermediate gauge bosonEffective coupling constantPartícules (Física nuclear)Standard ModelNeutral weak currentelectroweak theory Z boson DELPHI ALEPH OPAL L30103 physical sciencesANGLE BHABHA SCATTERINGCROSS-SECTION ASYMMETRYSEMILEPTONIC BRANCHING RATIOS010306 general physicsTOP-QUARK MASSEffective coupling constantsDELPHICoupling constantElectron–positron physics010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyFermionCARLO EVENT GENERATORTop quarkW-BOSON MASSFORWARD-BACKWARD ASYMMETRY FERMION-PAIR PRODUCTION HADRONIC-Z-DECAYS TOP-QUARK MASS ANGLE BHABHA SCATTERING W-BOSON MASS CROSS-SECTION ASYMMETRY Z-LINE-SHAPE SEMILEPTONIC BRANCHING RATIOS CARLO EVENT GENERATOR[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]Experimental High Energy PhysicsElectron–positron physicW bosonHigh Energy Physics::ExperimentFIS/04 - FISICA NUCLEARE E SUBNUCLEAREHADRONIC-Z-DECAYSPHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS
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