0000000000326683

AUTHOR

Franco Alhaique

showing 2 related works from this author

Guar gum/borax hydrogel: Rheological, low field NMR and release characterizations

2013

Guar gum (GG) and Guar gum/borax (GGb) hydrogels are studied by means of rheology, Low Field Nuclear Magnetic Resonance (LF NMR) and model drug release tests. These three approaches are used to estimate the mesh size (ζ) of the polymeric network. A comparison with similar Scleroglucan systems is carried out. In the case of GGb, the rheological and Low Field NMR estimations of ζ lead to comparable results, while the drug release approach seems to underestimate ζ. Such discrepancy is attributed to the viscous effect of some polymeric chains that, although bound to the network to one end, can freely fluctuate among meshes. The viscous drag exerted by these chains slows down drug…

Low field NMRMaterials sciencePolymers and PlasticsField (physics)General Chemical EngineeringDiffusionTransport processeslcsh:Chemical technologyPolymer Gels; Rheology; Low Field NMR; Transport processes; Mesh-sizechemistry.chemical_compoundRheologylcsh:TA401-492Materials ChemistryPolymer Gellcsh:TP1-1185Physical and Theoretical ChemistryComposite materialTransport processeGuar gumBoraxPolymer gelsOrganic ChemistryMesh-sizeLow field nuclear magnetic resonanceLow Field NMRlow field nmr; mesh-size; polymer gels; rheology; transport processesChemical engineeringchemistrySettore CHIM/09 - Farmaceutico Tecnologico ApplicativoSelf-healing hydrogelsViscous effectlcsh:Materials of engineering and construction. Mechanics of materialsRheologyExpress Polymer Letters
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Conformational analysis of α,β-poly(N-hydroxyethyl)-dl-aspartamide (PHEA) and α,β-polyasparthydrazide (PAHy) polymers in aqueous solution

1998

Abstract α,β-Poly(N-hydroxyethyl)- dl -aspartamide (PHEA) and α,β-polyasparthydrazide (PAHy) are synthetic polymers previously studied for biomedical applications. We report here the results of a small-angle X-ray scattering analysis carried out on these two macromolecules in aqueous solution. The data obtained indicate that the two polymers assume remarkably different conformations in aqueous solution, although the backbone is supposed to be the same for the two chains. PHEA can be represented by a random coil conformation, whereas PAHy can be described in terms of an elliptical cylinder characterized by an almost planar structural arrangement with the backbone refolded on itself in a fash…

chemistry.chemical_classificationAqueous solutionElliptical cylinderPolymers and PlasticsChemistryHydrogen bondSmall-angle X-ray scatteringGlobular proteinOrganic ChemistryPolymerRandom coilPolymer chemistryMaterials ChemistryMacromoleculePolymer
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