0000000000326892
AUTHOR
Annette Queißer-wahrendorf
Angeborene körperliche Anomalien: Epidemiologie
In Deutschland werden bei etwa jedem 15. Neugeborenen grose Fehlbildungen (z. B. Spina bifida, Lippen-Kiefer-Gaumen-Spalte) diagnostiziert, ungefahr ein Funftel davon sind schwer und lebensbedrohlich. Kinder mit angeborenen Fehlbildungen machen etwa ein Drittel aller padiatrischen stationaren Aufnahmen aus. Die angeborenen Entwicklungsdefekte sind die haufigste Ursache der neonatalen Mortalitat und benotigen haufig intensive lebenslange Behandlungen, die hohe Kosten verursachen. Diese Kinder sind somit eine sehr wichtige Patientengruppe in der Padiatrie.
Ramadan During Pregnancy – Fasting, Nutrition, Sleep Patterns and Offspring Health at Birth: A Cross-Sectional Study
Background: Intrauterine exposure to Ramadan is associated with adverse offspring health outcomes. Yet, the dynamics behind these associations remain largely unexplored. We investigate if maternal intermittent fasting or other lifestyle changes during Ramadan affect birth outcomes, and determine whether nutritional and sleep behavior during non-fasting hours influences the fasting-birth weight association. Methods: Linear regressions are estimated using OLS to identify the associations between fasting, sleep behavior, sweets consumption and birth weight, 5-minute APGAR score and gestational age. Interaction terms between fasting and other behaviors are included to explore the potential mode…
Twenty-year trends in the prevalence of Down syndrome and other trisomies in Europe : impact of maternal age and prenatal screening
This study examines trends and geographical differences in total and live birth prevalence of trisomies 21, 18 and 13 with regard to increasing maternal age and prenatal diagnosis in Europe. Twenty-one population-based EUROCAT registries covering 6.1 million births between 1990 and 2009 participated. Trisomy cases included live births, fetal deaths from 20 weeks gestational age and terminations of pregnancy for fetal anomaly. We present correction to 20 weeks gestational age (ie, correcting early terminations for the probability of fetal survival to 20 weeks) to allow for artefactual screening-related differences in total prevalence. Poisson regression was used. The proportion of births in …