0000000000326966

AUTHOR

Peter Konstantin Kurotschka

showing 2 related works from this author

An umbrella review of systematic reviews with meta-analyses evaluating positive and negative outcomes of Hydroxychloroquine and chloroquine therapy

2021

Background & aims: Hydroxychloroquine (HCQ) and chloroquine (CQ) are anti-malarial drugs frequently used in the rheumatologic field. They were recently identified as potential therapeutic options for Coronavirus Disease (COVID-19). The present study aims to map and grade the diverse health outcomes associated with HCQ/CQ using an umbrella review approach. Methods: Umbrella review of systematic reviews of observational and intervention studies. For observational studies, random-effects summary effect size, 95% confidence interval, and 95% prediction interval were estimated. We also assessed heterogeneity, evidence for small-study effect, and evidence for excess significance bias. The quality…

0301 basic medicineMicrobiology (medical)medicine.medical_specialtyhydroxychloroquine030106 microbiologyDiseaseReviewlcsh:Infectious and parasitic diseaseslaw.inventionchloroquine03 medical and health sciences0302 clinical medicinesystematic reviewRandomized controlled triallawChloroquineInternal medicineDiabetes mellitusChloroquine; COVID-19; Hydroxychloroquine; umbrella review; COVID-19; Chloroquine; Humans; Hydroxychloroquine; SARS-CoV-2medicineHumanslcsh:RC109-216030212 general & internal medicineumbrella reviewbusiness.industrySARS-CoV-2COVID-19HydroxychloroquineChloroquineGeneral Medicinemedicine.diseaseConfidence intervalCOVID-19 Drug TreatmentInfectious DiseasesSystematic reviewObservational studybusinessmedicine.drugHumanHydroxychloroquine
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Italian young doctors’ knowledge, attitudes and practices on antibiotic use and resistance: A national cross-sectional survey

2020

Abstract Objectives Antimicrobial resistance (AMR) is one of the major health issues worldwide. Clinicians should play a central role to fight AMR, and medical training is a pivotal issue to combat it; therefore, assessing levels of knowledge, attitudes and practices among young doctors is essential for future antimicrobial stewardship (AMS) programmes. Methods A nationwide, cross-sectional, multicentre survey was conducted in Italy. A descriptive analysis of knowledge and attitudes was performed, along with a univariate and multivariate analysis of their determinants. Results Overall, 1179 young doctors accessed the survey and 1055 (89.5%) completed all sections. Regarding the knowledge se…

0301 basic medicineMicrobiology (medical)Health Knowledge Attitudes Practicemedicine.medical_specialtyMultivariate analysisCross-sectional study030106 microbiologyImmunologySpecialtyResistance (psychoanalysis)Antimicrobial stewardshipMultidrug resistanceAntimicrobial resistanceMicrobiology03 medical and health sciences0302 clinical medicinePhysiciansSurvey Antimicrobial resistance Antimicrobial stewardship Multidrug resistance Knowledge Attitudes and practices KAPHumansImmunology and AllergyAntimicrobial stewardshipMedicine030212 general & internal medicineSurveyCurriculumDescriptive statisticsAttitudes and practicesbusiness.industryQR1-502Anti-Bacterial AgentsCross-Sectional StudiesKnowledgeItalyFamily medicinebusinessInclusion (education)Journal of Global Antimicrobial Resistance
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