0000000000330847

AUTHOR

Meryem Berrichi

showing 2 related works from this author

Zizyphin modulates calcium signalling in human taste bud cells and fat taste perception in the mouse.

2017

Zizyphin, isolated from Zizyphus sps. leaf extracts, has been shown to modulate sugar taste perception, and the palatability of a sweet solution is increased by the addition of fatty acids. We, therefore, studied whether zizyphin also modulates fat taste perception. Zizyphin was purified from edible fruit of Zizyphus lotus L. Zizyphin induced increases in [Ca2+]i in human taste bud cells (hTBC). Zizyphin shared the endoplasmic reticulum Ca2+ pool and also recruited, in part, Ca2+ from extracellular environment via the opening of store-operated Ca2+ (SOC) channels. Zizyphin exerted additive actions on linoleic acid-induced increases in [Ca2+]i in these cells, indicating that zizyphin does no…

Male0301 basic medicinemedicine.medical_specialtyTasteLinoleic acidBiologyPeptides CyclicReceptors G-Protein-CoupledMice03 medical and health scienceschemistry.chemical_compoundAlkaloids0302 clinical medicineTAS1R3Internal medicinesweet tastemedicineAnimalsHumansPharmacology (medical)Calcium SignalingPalatabilityCells CulturedZizyphus lotus LCalcium signalingMice KnockoutPharmacologychemistry.chemical_classificationPlant ExtractsTaste PerceptionGPR120Fatty acid[ SDV.SP.PHARMA ] Life Sciences [q-bio]/Pharmaceutical sciences/PharmacologyZiziphusTaste BudsDietary FatsG protein-coupled bile acid receptorfat tastezizyphinMice Inbred C57BL030104 developmental biologyEndocrinologyBiochemistrychemistry030217 neurology & neurosurgery
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Zizyphus lotus L. fruit attenuates obesity-associated alterations: in vivo mechanisms

2019

Zizyphus lotus L., ZL is a Mediterranean plant and widely consumed for its beneficial medicinal properties. Objective: We assessed the effects of ZL fruit on diet-induced obesity. Materials and met...

Traditional medicinebiologyPhysiologyInsulinmedicine.medical_treatmentfungiLotusfood and beverages030209 endocrinology & metabolismHigh fat dietInflammationGeneral Medicinebiology.organism_classificationmedicine.diseaseObesity03 medical and health sciences0302 clinical medicineIn vivo030220 oncology & carcinogenesisPhysiology (medical)medicinemedicine.symptomArchives of Physiology and Biochemistry
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