0000000000331476
AUTHOR
Hafiz Ahmed
showing 3 related works from this author
Structural and functional diversity of the lectin repertoire in teleost fish: Relevance to innate and adaptive immunity
2011
Protein–carbohydrate interactions mediated by lectins have been recognized as key components of innate immunity in vertebrates and invertebrates, not only for recognition of potential pathogens, but also for participating in downstream effector functions, such as their agglutination, immobilization, and complement-mediated opsonization and killing. More recently, lectins have been identified as critical regulators of mammalian adaptive immune responses. Fish are endowed with virtually all components of the mammalian adaptive immunity, and are equipped with a complex lectin repertoire. In this review, we discuss evidence suggesting that: (a) lectin repertoires in teleost fish are highly dive…
Evidence of Heavy Methylation in the Galectin 3 Promoter in Early Stages of Prostate Adenocarcinoma: Development and Validation of a Methylated Marke…
2009
Galectins, soluble intracellular and extracellular β-galactoside–binding proteins, are known to be involved in the progression and metastasis of various cancers, including prostate adenocarcinoma, but the detailed mechanism of their biological roles remains elusive. In the prostate cancer cell lines PC-3 and DU-145, galectin 3 (gal3) is present at normal levels, whereas in LNCaP, its expression is silenced. In LNCaP, the gal3 promoter was heavily methylated, whereas PC-3 or DU-145 cells showed negligible or no methylation in the gal3 promoter indicating a negative correlation between gal3 promoter methylation and its expression. On immunohistochemical analysis of normal and tumor prostate t…
Dynamical model identification of population of oysters for water quality monitoring
2014
International audience; The measurements of valve activity in a population of bivalves under natural environmental conditions (16 oysters in the Bay of Arcachon, France) are used for a physiological model identification. A nonlinear auto-regressive exogenous (NARX) model is designed and tested. The model takes into account the influence of environmental conditions using measurements of the sunlight intensity, the moonlight and tide levels. A possible influence of the internal circadian/circatidal clocks is also analyzed. Through this application, it is demonstrated that the developed dynamical model can be used for estimation of the normal physiological rhythms of permanently immersed oyste…