0000000000332101
AUTHOR
J. Grevenstein
Correlative histologic and arthroscopic evaluation in rheumatoid knee joints.
The correlation between arthroscopic observations and histologic changes in rheumatoid arthritis is still controversial. Synovial samples of 21 knee joints in rheumatoid arthritis patients were comparatively investigated by endoscopy and histology. Biopsies were scored by an endoscopist and subsequently dissected. Different histochemical and immunocytochemical staining techniques were used to define inflammatory activity. Arthroscopic and histological values were compared by rating scales and variance analysis. Our study indicates that synovial biopsy is of diagnostic value in rheumatoid arthritis. However, its usefulness depends on the histochemical methods used. The results revealed highl…
Der Einfluß von N-Azetylglucosamin auf die Proteoglykansynthese normaler und arthrotischer Chondrozyten
Die Arthrose geht mit einem Verlust der biologischen Eigenschaften des Gelenk-Knorpels einher. Die Bildung der Hauptkomponenten der extrazellularen Matrix (Kollagen und Proteoglykane) ist beeintrachtigt. Zur Analyse der metabolischen Veranderungen im Verlaufe verschiedener Arthrosestadien wurden biochemische Analysen an kultivierten Chondrozyten durchgefuhrt Da Chondrozyten im Verlaufe der Subkultivierung entdifferenzieren, war es erforderlich, sie zur Redifferenzierung in eine Agarosematrix zu uberfuhren. Aus fruheren Untersuchungen ist bekannt, das durch diese Technik der ursprungliche Phanotyp der Knorpelzelle wiederhergestellt werden kann.
Die Röntgendigitalanlage als Instrument zur kinematischen Untersuchung der Schulter — Eine Untersuchung zur Strahlenbelastung - Digital Radiography as a Tool for the Kinematic Analysis of the Shoulder Joint - A Study of Radiation Dose
The radiation exposure during biomechanical investigation of the shoulder joint done with a digital radiography system (Polytron 1000 VR - Siemens) was measured experimentally. Total radiation dose and surface dose were determined by phantom measurements. The radiation exposure per image is about 1/6 to 1/7 of that of a conventional study. The digital radiography system used is thus suitable for kinesiologic studies of large joints in healthy volunteers.