0000000000336180

AUTHOR

E. Küstner

showing 2 related works from this author

Indoor air pollutants stimulate interleukin-8-specific mRNA expression and protein secretion of alveolar macrophages.

1998

Indoor air pollutants may cause inflammatory changes of the airways and adjacent pulmonary tissue. After phagocytosis of inhaled particles alveolar macrophages (AM) release chemotactic mediators capable of attracting inflammatory cells into the lung tissue. To evaluate these mechanisms further peripheral blood mononuclear cells (PBMNC) and human AM (freshly recovered from the lower respiratory tract) were exposed to the indoor particles Soot FR 101 and Printex 90, the asbestos fiber Chrysotile B, and titanium dioxide (TiO2) at concentrations of 10 or 50 microg/10(6) cells for up to 8 h. The migration of granulocytes into the conditioned supernatants of AM and PBMNC was quantified by chemota…

Pulmonary and Respiratory MedicineGranulocyte migrationAdultMaleChemokineBiologyGranulocytePeripheral blood mononuclear cellPolymerase Chain ReactionMicrobiologyMacrophages AlveolarmedicineHumansInterleukin 8RNA MessengerAgedAir PollutantsLungInterleukin-8InterleukinMolecular biologyChemotaxis Leukocytemedicine.anatomical_structureAir Pollution Indoorbiology.proteinLeukocytes MononuclearFemaleBronchoalveolar Lavage FluidChemotaxis assayLung
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Vergleich des Hypoglykämieempfindens und der hormonellen Gegenregulation während einer kontrollierten Hypoglykämie: Ein Beitrag zur Diagnostik des Hy…

2008

BACKGROUND AND OBJECTIVE Diabetics with abnormal hypoglycaemia awareness cannot recognize hypoglycaemic symptoms early and adequately enough to respond, thus endangering in everyday life not only themselves but also others. Thus it is important to diagnose such symptoms early and assess the extent to which the diabetic is at risk of severe hypoglycaemia. This study was designed to contribute to the evaluation of hypoglycaemia awareness in type 1 (IDDM) diabetics. PATIENTS AND METHODS In 57 diabetics (IDDM) awareness of typical hypoglycaemic warning symptoms and of hormonal counterregulation were tested during controlled induced hypoglycaemia. A questionnaire was used to measure at fixed tim…

medicine.medical_specialtyPediatricsendocrine system diseasesbusiness.industrynutritional and metabolic diseasesGeneral MedicineHypoglycemiaGlucose clamp techniquemedicine.diseaseGlucagonArousalEndocrinologyEpinephrineInternal medicineDiabetes mellitusCohortmedicinebusinessmedicine.drugCohort studyDMW - Deutsche Medizinische Wochenschrift
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